Results 81 to 90 of about 232,783 (214)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

SARS-CoV-2 spike opening dynamics and energetics reveal the individual roles of glycans and their collective impact. [PDF]

Commun Biol, 2022
Pang YT, Acharya A, Lynch DL, Pavlova A, Gumbart JC.   +4 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Editorial: Professional and scientific societies impacting diversity, equity and inclusion in STEMM

Frontiers in Sociology, 2023
Verónica A. Segarra, Verónica A. Segarra, Verónica A. Segarra, Verónica A. Segarra, Candice M. Etson, Candice M. Etson, Candice M. Etson   +6 more
doaj   +1 more source

Catalyzing Organizational Change for Equity in Graduate Education: A Case Study of Adopting Collective Impact in a College of Engineering

Education Sciences
Graduate education in engineering is an extremely challenging, complex entity that is difficult to change. The purpose of this exploratory research paper was to investigate the applicability of the Collective Impact framework, which has been used within ...
Walter C. Lee, Teirra K. Holloman, David B. Knight, Natali Huggins, Holly M. Matusovich, Julia Brisbane   +5 more
doaj   +1 more source

Implementation evaluation of a collective impact initiative to promote adolescent health in Oklahoma County, USA. [PDF]

BMC Public Health, 2022
Garney WR, Panjwani S, Wilson K, Garcia KE, Fore S, Lautner SC, Lang L, Criswell B, Mathews R.   +8 more
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Measuring Collective Impact of Extension Programs Addressing Substance Use and Mental Health

Journal of Human Sciences and Extension
Extension excels at working across program areas and disciplinary boundaries inside and outside land-grant institutions to address complex social issues within communities.
Omolola A. Adedokun, Olumuyiwa M. Desmennu , Alex Elswick, Nichole Huff , Brooke Jenkins, Katherine Jury, Heather Norman-Burgdolf   +6 more
doaj   +1 more source

Correction to: The association of reduced left ventricular strains with increased extracellular volume and their collective impact on clinical outcomes. [PDF]

J Cardiovasc Magn Reson, 2021
Jin C, Weber J, Singh H, Gliganic K, Cao JJ.   +4 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source