Results 31 to 40 of about 378,378 (264)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Are the healers healthy? Exploring non-communicable diseases among healthcare workers in Ajman, United Arab Emirates

BMC Public Health
Background Non-communicable diseases (NCDs), particularly cardiovascular diseases, are a major cause of global mortality. In the Gulf Cooperation Council (GCC) nations, healthcare workers face increased risks of obesity, hypertension, and diabetes due to
Sandhra Treesa Santhosh, Abubakker Siddiq Mohamed Hameed, Anugraha Lisa Ciju, Aaesha Rannath, Syeda Kaunain Fatima, Janet Chichu James, Mohammed Nayeem Shaji, Ehab M Esheiba, Jayadevan Sreedharan, Jayakumary Muttappallymyalil   +9 more
doaj   +1 more source

Awareness and Knowledge about Probiotics among College Students

Journal of Pure and Applied Microbiology, 2019
Probiotics are important for maintaining good gut health. In the present scenario when drug resistance among pathogenic bacteria is increasing, it has become of utmost importance for everyone to keep healthy gut microbiome.
Richa Sharma, Siddharth Gupta, Deesha Gupta, Pawan Kumar Kushwaha   +3 more
doaj   +1 more source

Analysis and Research on the Rehabilitation Effect of Physical Exercise on College Students’ Mental Depression Based on Multidimensional Data Mining

Occupational Therapy International, 2022
In order to explore the physical exercise and psychological changes of college students, this study adopts the method of multidimensional data mining, taking 23,146 undergraduates from a university in Guangzhou, Guangdong Province, as the research object.
Wen Zou
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Fostering innovation and building youth capacity in global health: design, implementation, and evaluation of a youth-led digital health hackathon

BMC Medical Education
Background African countries face significant challenges in their healthcare systems, including inadequate human resources, insufficient budgetary allocation, and poor leadership and management.
Victor Oluwafemi Femi-Lawal, Olaoluwaposi Emmanuel Ogunlana, Temilola Aderemi, Olutola Vivian Awosiku, Stephen Igwe, Adetayo Adetokun, Umulkhairah Onyioiza Arama, Marvellous Adelaja, Oluwagbemisola Akinjobi, Gift Dansu, Peter Abolarin, Chijioke Mgbeobukwa, Sean Anointed   +12 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Using the Exercise Is Medicine® on Campus Platform to Assess College Students’ Practice of Physical Activity in a Rural Setting

Journal of the Georgia Public Health Association, 2016
Background: The college setting offers public health educators and exercise scientists a favorable environment to implement wide-spread change in levels of physical activities. With over two-thirds of all adults in the U.S.
Bridget Melton, Jazmin Williamson, Helen Bland, Jian Zhang   +3 more
doaj   +1 more source