Results 51 to 60 of about 9,957,383 (309)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Analysis of cases of suicide by self-immolation in the post-mortem material of the Department of Forensic Medicine in Cracow 

Archives of Forensic Medicine and Criminology
Aim of the study: Analysis of self-immolation cases and distribution of the resulting burns and their degree.Material and methods: The study included 16 cases from the Department of Forensic Medicine,
Katarzyna Klimaszewska, Patrycja Jakubiec, Aneta Kotlarek, Wiktoria Wojturska, Zuzanna Buś, Aleksandra Nosal, Tomasz Konopka   +6 more
doaj   +1 more source

Yearbook (Gettysburg College); Gettysburg College spectrum; Gettysburg College yearbook

, 1899
The Spectrum yearbook contains images and text created by students during their time at Gettysburg College. Offensive content can be found on these pages and does not represent the College’s values.
Gettysburg College
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Does yoga shape body, mind and spiritual health and happiness: Differences between yoga practitioners and college students

International Journal of Yoga, 2010
Background/Aims: To assess the body, mind and spirit differences between yoga students compared with college students. Materials and Methods: Mind, body and spirit survey instruments administered to the two groups.
Monk-Turner Elizabeth, Turner Charlie
doaj  

First-Generation College Students

Journal of College Orientation, Transition, and Retention, 2013
First-generation students’ transitions are particularly important to their success in college. Though attention to and support for first-generation students on college campuses have increased in recent decades, these efforts remain campus-centric ...
Elizabeth Buffy Stoll
doaj   +1 more source

Yearbook (Gettysburg College); Gettysburg College spectrum; Gettysburg College yearbook;

, 1951
The Spectrum yearbook contains images and text created by students during their time at Gettysburg College.
Gettysburg College
core