Results 71 to 80 of about 6,770,515 (359)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Analysis and Research on the Rehabilitation Effect of Physical Exercise on College Students’ Mental Depression Based on Multidimensional Data Mining

Occupational Therapy International, 2022
In order to explore the physical exercise and psychological changes of college students, this study adopts the method of multidimensional data mining, taking 23,146 undergraduates from a university in Guangzhou, Guangdong Province, as the research object.
Wen Zou
doaj   +1 more source

Mental disorders among college students in the WHO World Mental Health Surveys

Psychological Medicine, 2016
Background Although mental disorders are significant predictors of educational attainment throughout the entire educational career, most research on mental disorders among students has focused on the primary and secondary school years.
R. P. Auerbach, J. Alonso, W. Axinn, P. Cuijpers, D. Ebert, J. G. Green, I. Hwang, R. Kessler, H. Liu, P. Mortier, M. Nock, S. Pinder-Amaker, N. Sampson, S. Aguilar-Gaxiola, A. Al-Hamzawi, L. Andrade, C. Benjet, J. Caldas-de-Almeida, K. Demyttenaere, S. Florescu, G. de Girolamo, O. Gureje, J. Haro, E. Karam, A. Kiejna, V. Kovess-Masfety, S. Lee, J. Mcgrath, Siobhan O'Neill, B. Pennell, K. Scott, M. ten Have, Y. Torres, A. Zaslavsky, Z. Zarkov, R. Bruffaerts   +35 more
semanticscholar   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Fostering innovation and building youth capacity in global health: design, implementation, and evaluation of a youth-led digital health hackathon

BMC Medical Education
Background African countries face significant challenges in their healthcare systems, including inadequate human resources, insufficient budgetary allocation, and poor leadership and management.
Victor Oluwafemi Femi-Lawal, Olaoluwaposi Emmanuel Ogunlana, Temilola Aderemi, Olutola Vivian Awosiku, Stephen Igwe, Adetayo Adetokun, Umulkhairah Onyioiza Arama, Marvellous Adelaja, Oluwagbemisola Akinjobi, Gift Dansu, Peter Abolarin, Chijioke Mgbeobukwa, Sean Anointed   +12 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Using the Exercise Is Medicine® on Campus Platform to Assess College Students’ Practice of Physical Activity in a Rural Setting

Journal of the Georgia Public Health Association, 2016
Background: The college setting offers public health educators and exercise scientists a favorable environment to implement wide-spread change in levels of physical activities. With over two-thirds of all adults in the U.S.
Bridget Melton, Jazmin Williamson, Helen Bland, Jian Zhang   +3 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Negative life events and college students’ adjustment: the mediating role of self-esteem and the moderating role of grade

Frontiers in Psychology
The present research explored the relationship among negative life events, self-esteem, grade, and adjustment of college students. In total, 1,717 college students were investigated by the adolescent life events scale, Rosenberg self-esteem inventory ...
Xiaoshan Quan, Ji Sun, Ji Sun
doaj   +1 more source