Results 171 to 180 of about 684,916 (242)

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers   +5 more
wiley   +1 more source

Mass Spectrometry in Authentication and Forensic Approaches for Determining the Origin of Hazardous Chemicals

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Identification of a chemical agent yields insights into its physicochemical properties. By examining the intrinsic characteristics and environment of a compound, information about its history can be gathered. The main objective of authentication/forensic approaches to chemicals is to trace the history of the compound's origin, regardless of ...
Carla Orlandi   +6 more
wiley   +1 more source

Falls in Huntington's Disease: A Cross‐Sectional Analysis of Clinical Features and Potential Contributors

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Falls occur across all stages of Huntington's disease (HD) and are associated with poor quality of life and injury. However, there is limited information on falls in HD. Objective The aim was to investigate the clinical features potentially associated with falls in HD. Methods We conducted a cross‐sectional, analytical observational
Arthur Pena Ferreira   +5 more
wiley   +1 more source

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