Abstract Objective Individuals with Down syndrome (DS) face an ultra‐high risk of Alzheimer's disease (AD). Within this continuum, Progressive Myoclonus Epilepsy (PME) has emerged as a marker of advanced neurodegeneration. Building on our 2014 characterization of this syndrome, we aimed to define its long‐term natural history and pathological substrate.
Giuseppe d'Orsi +6 more
wiley +1 more source
Virtual social interaction reveals that the dorsal habenula-IPN pathway is essential for targeting the opponent. [PDF]
Islam T +4 more
europepmc +1 more source
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka +4 more
wiley +1 more source
Artificial intelligence driven approach for securing backup data and enhancing cyber resilience in sustainable smart infrastructure. [PDF]
Kumar B +5 more
europepmc +1 more source
Revolutionizing Healthcare With Paper‐Based Nucleic Acid Testing
This work summarizes strategies to enhance paper‐based devices for nucleic acid testing. Key approaches include optimizing paper platforms, improving nucleic acid amplification, and refining labeling/signaling methods. These advancements aim to boost sensitivity, speed, and usability, making paper‐based diagnostics more effective for point‐of‐care ...
Hong Zhang +8 more
wiley +1 more source
A hybrid hash framework for post quantum secure zero knowledge identification. [PDF]
Bhadane S +3 more
europepmc +1 more source
Multi‐Energy‐Driven Photocatalysis: Mechanism, Progress, and Perspective
Photocatalysis technology can be utilized in water splitting, carbon dioxide reduction, pollutant degradation, and chemical synthesis. Introducing external energy fields, including thermal energy, electrical energy, magnetic energy, mechanical energy, and microwave energy, has been considered as a promising method to improve photocatalytic performance ...
Liangcheng Xu +5 more
wiley +1 more source
Kinematic and biomechanical estimates of head and neck loading during the long attack in IGP protection work dogs. [PDF]
Vilar JM +4 more
europepmc +1 more source
Mesozoic–Cenozoic Thermochronology of the Tarim–Southern Tianshan System, NW China
Tectonothermal history of the Tarim–Southern Tianshan system compared with the major tectonic events at far‐field plate margins. ABSTRACT The Tarim Basin, an oil‐bearing basin in northwest China, is tectonically and sedimentologically linked to the Southern Tianshan Orogenic Belt.
Shuangfeng Zhao +4 more
wiley +1 more source
A Kyber-Based Lightweight Cloud-Assisted Authentication Scheme for Medical IoT. [PDF]
Yan H, Wang Z, Lin L, Sun J, Liu S.
europepmc +1 more source

