Results 81 to 90 of about 11,539 (251)

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

Optimizing Stratification in Binary Colloidal Supraparticles

Advanced Science, EarlyView.
Supraparticles from binary particle populations show stratification when dried at high Péclet numbers. In spray‐dried systems at high initial particle concentration and fast drying conditions optimal combinations of particle size ratios and volume fractions that produce maximal stratification are found both in experiment and simulation, contrasting the
Frederic Rudlof, Silas Wolf, Sonja Schaller, Jonathan Martín González, Carsten Schilde, Nicolas Vogel   +5 more
wiley   +1 more source

Preimage and collision attacks on reduced Ascon using algebraic strategies

Cybersecurity
Ascon, a family of algorithms that supports hashing and authenticated encryption, is the winner of the NIST Lightweight Cryptography Project. In this paper, we propose an improved preimage attack against 2-round Ascon-XOF-64 with a complexity of $$2^{33}$
Qinggan Fu, Ye Luo, Qianqian Yang, Ling Song   +3 more
doaj   +1 more source

Cryptanalysis of 48-step RIPEMD-160

IACR Transactions on Symmetric Cryptology, 2017
In this paper, we show how to theoretically compute the step differential probability of RIPEMD-160 under the condition that only one internal variable contains difference and the difference is a power of 2.
Gaoli Wang, Yanzhao Shen, Fukang Liu
doaj   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Improved meet-in-the-middle collision attack on round-reduced Xoodyak

Cybersecurity
With the growing prevalence of compact and resource-constrained computing devices, demand for lightweight cryptographic schemes is burgeoning. Xoodyak-Hash, a lightweight hash function that entered the final round of the NIST Lightweight Cryptography ...
Mingyao Gao, Shun Zhang, Jie Guan, Tairong Shi, Senpeng Wang   +4 more
doaj   +1 more source

Quantum Random Oracle Model for Quantum Public-Key Encryption

IEEE Access, 2019
Random oracle model is a general security analysis tool for rigorous security proof and effective cryptographic protocol design. In the quantum world, the attempts of constructing a quantum random oracle (QRO) have been made, such as quantum-accessible ...
Tao Shang, Ranyiliu Chen, Qi Lei
doaj   +1 more source

Emergent Spinning and Orbital Motion in Clustered Wind‐Assisted Flyers

Advanced Science, EarlyView.
Inspired by natural snowflake geometries, paper‐cut flyers exhibit geometry‐defined spinning and orbital motions during cluster formation in a wind tunnel. Collective flights of multiple paperflakes reveal dynamic clustering, fragmentation, and continuously evolving spin behaviors.
Bingnan Zhou, Rahul Chand, Fahad Ahmed Korai, Jianfeng Yang, Valtteri Savonen, Fan Liu, Qi Yang, Hao Zeng   +7 more
wiley   +1 more source

A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43

Advanced Science, EarlyView.
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg, Anastasia Lopatina, Hao Ruan, Tom Scheidt, Simone Mosna, Emre Pekbilir, Julia Bieber, Frank Schäfer‐Depoix, Katharina Landfester, Carla Schmidt, Martin M. Möckel, Svenja Morsbach, Friederike Schmid, Dorothee Dormann, Lukas Stelzl, Martin Girard, Edward A. Lemke   +16 more
wiley   +1 more source

Collision Attacks on AES-192/256, Crypton-192/256, mCrypton-96/128, and Anubis

Journal of Applied Mathematics, 2013
At AES’00, a collision attack on 7-round reduced AES was proposed. In this paper, we apply this idea to seven SPN block ciphers, AES-192/256, Crypton-192/256, mCrypton-96/128, and Anubis.
Jinkeon Kang, Kitae Jeong, Jaechul Sung, Seokhie Hong, Kyungho Lee   +4 more
doaj   +1 more source