Results 1 to 10 of about 279,038 (339)
Assigning Co-Regulated Human Genes and Regulatory Gene Clusters
Cells, 2021 Elucidating the role of genetic variation in the regulation of gene expression is key to understanding the pathobiology of complex diseases which, in consequence, is crucial in devising targeted treatment options.
Tobias Strunz +3 more
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A New Set of Golden-Gate-Based Organelle Marker Plasmids for Colocalization Studies in Plants
Plants, 2022 In vivo localization of proteins using fluorescence-based approaches by fusion of the protein of interest (POI) to a fluorescent protein is a cost- and time-effective tool to gain insights into its physiological function in a plant cell.
Hagen Stellmach +4 more
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The Journal of Poultry Science, 2023 The aim of this study was to identify the histological features of chicken enteroendocrine cells before and after hatching. Tissue samples from the duodenum, proximal and distal parts of the jejunum and ileum, cecum and colorectum were collected from the
Md. Al amin +3 more
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The missing link between genetic association and regulatory function
eLife, 2022 The genetic basis of most traits is highly polygenic and dominated by non-coding alleles. It is widely assumed that such alleles exert small regulatory effects on the expression of cis-linked genes.
Noah J Connally +8 more
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Benchmarking post-GWAS analysis tools in major depression: Challenges and implications
Frontiers in Genetics, 2022 Our knowledge of complex disorders has increased in the last years thanks to the identification of genetic variants (GVs) significantly associated with disease phenotypes by genome-wide association studies (GWAS).
Judith Pérez-Granado +4 more
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Leveraging primate-specific genomic information for genetic studies of complex diseases
Frontiers in Bioinformatics, 2023 Genomic changes specific to higher primates are regarded as primate-specific genomic information (PSI). Using PSI to inform genetic studies is highly desirable but hampered by three factors: heterogeneity among PSI studies, lack of integrated profiles of
Wen-Hua Wei +3 more
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Cells, 2020 Though midline1 interacting protein 1 (MID1IP1) was known as one of the glucose-responsive genes regulated by carbohydrate response element binding protein (ChREBP), the underlying mechanisms for its oncogenic role were never explored.
Ji Hoon Jung +7 more
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Colocalization of neurons in optical coherence microscopy and Nissl-stained histology in Brodmann’s area 32 and area 21 [PDF]
, 2018 Published in final edited form as: Brain Struct Funct. 2019 January ; 224(1): 351–362. doi:10.1007/s00429-018-1777-z.Optical coherence tomography is an optical technique that uses backscattered light to highlight intrinsic structure, and when applied to
Augustinack, Jean C. +7 more
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Frontiers in Genetics, 2023 Background: Genome-wide association studies (GWAS) for corneal resistance factor (CRF) have identified 100s of loci and proved useful to uncover genetic determinants for keratoconus, a corneal ectasia of early-adulthood onset and common indication of ...
Xinyi Jiang +3 more
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ABCC6 is a basolateral plasma membrane protein [PDF]
, 2013 RATIONALE:: ABCC6 plays a crucial role in ectopic calcification; mutations of the gene cause pseudoxanthoma elasticum and general arterial calcification of infancy.
Apana, A. +11 more
core +4 more sources