Results 91 to 100 of about 279,038 (339)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Visualizing caveolin-1 and HDL in cholesterol-loaded aortic endothelial cells

Journal of Lipid Research, 2003
Caveolae are vesicular invaginations of the plasma membranes that regulate signal transduction and transcytosis, as well as cellular cholesterol homeostasis. Our previous studies indicated that the removal of cholesterol from aortic endothelial cells and
W.T. Chao, S.S. Fan, J.K. Chen, V.C. Yang   +3 more
doaj   +1 more source

Mobilization of Antibiotic Resistance: Are Current Approaches for Colocalizing Resistomes and Mobilomes Useful?

Frontiers in Microbiology, 2020
Antimicrobial resistance (AMR) poses a global human and animal health threat, and predicting AMR persistence and transmission remains an intractable challenge.
Ilya B. Slizovskiy, Kingshuk Mukherjee, Christopher J. Dean, Christina Boucher, Noelle R. Noyes   +4 more
doaj   +1 more source

Localizations, colocalizations and non additive ∗-objects [PDF]

Semigroup Forum, 2010
16 pages ...
openaire   +3 more sources

Colocalized Vitiligo and Psoriasis

Journal of Pharmaceutical Research & Reports, 2020
Psoriasis is a chronic inflammatory cutaneous disorder characterized by abnormal epidermal growth and differentiation, presenting as red, scaly patches, papules, and plaques.
S Belmourida, H Palamino
openaire   +1 more source

Quantifying receptor trafficking and colocalization with confocal microscopy.

Methods, 2017
Confocal microscopy is a powerful tool for the study of cellular receptor trafficking and endocytosis. Unbiased and robust image analysis workflows are required for the identification, and study, of aberrant trafficking.
Jeremy A. Pike, I. Styles, J. Rappoport, J. Heath   +3 more
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Closing the multichannel gap through computational reconstruction of interaction in super-resolution microscopy

Patterns
Summary: Cellular function is defined by pathways that, in turn, are determined by distance-mediated interactions between and within subcellular organelles, protein complexes, and macromolecular structures.
Ben Cardoen, Hanene Ben Yedder, Ivan Robert Nabi, Ghassan Hamarneh   +3 more
doaj   +1 more source

Lipid imaging by gold cluster time-of-flight secondary ion mass spectrometry: application to Duchenne muscular dystrophy

Journal of Lipid Research, 2005
Imaging with time-of-flight secondary ion mass spectrometry (TOF-SIMS) has expanded very rapidly with the development of gold cluster ion sources (Au3+).
David Touboul, Alain Brunelle, Frédéric Halgand, Sabine De La Porte, Olivier Laprévote   +4 more
doaj   +1 more source

Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding [PDF]

, 2010
Peer reviewedPublisher ...
Barabas, Klaudia, Cameron, Gary, Harkany, Tibor, Keimpema, Erik, Mackie, Ken, Morozov, Yury M, Torii, Masaaki, Tortoriello, Giuseppe, Watanabe, Masahiko, Yanagawa, Yuchio   +9 more
core   +1 more source