Results 21 to 30 of about 279,038 (339)
bioRxiv, 2020 Colocalization analysis has emerged as a powerful tool to uncover the overlapping of causal variants responsible for both molecular and complex disease phenotypes.
Abhay Hukku +5 more
semanticscholar +1 more source
Self-colocation: a colocation puzzle for endurantists [PDF]
Synthese, 2019 The recent literature on the nature of persistence features a handful of imaginative cases in which an object seems to colocate with itself. So far, discussion of these cases has focused primarily on how they defy the standard endurantist approaches to the problem of temporary intrinsics. But in this article, I set that issue aside and argue that cases
openaire +1 more source
Bin Packing with Colocations [PDF]
, 2017 Motivated by an assignment problem arising in MapReduce computations, we investigate a generalization of the Bin Packing problem which we call Bin Packing with Colocations Problem. We are given a weigthed graph G = (V, E), where V represents the set of items with positive integer weights and E the set of related (to be colocated) items, and an integer ...
Bermond, Jean-Claude +6 more
openaire +4 more sources
Frontiers in Neuroscience, 2021 The endocannabinoid and orexin neuromodulatory systems serve key roles in many of the same biological functions such as sleep, appetite, pain processing, and emotional behaviors related to reward.
Hye Ji J. Kim +7 more
doaj +1 more source
Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells [PDF]
, 2018 Estrogen receptor α (ERα) is expressed in tissues as diverse as brains and mammary glands. In breast cancer, ERα is a key regulator of tumor progression.
Acconcia +111 more
core +2 more sources
General Principles of Neuronal Co-transmission: Insights From Multiple Model Systems
Frontiers in Neural Circuits, 2019 It is now accepted that neurons contain and release multiple transmitter substances. However, we still have only limited insight into the regulation and functional effects of this co-transmission.
Erik Svensson +6 more
doaj +1 more source
The Roles of Membrane Rafts in CD32A-Mediated Phagocytosis [PDF]
, 2007 Membrane rafts are highly dynamic heterogeneous sterol- and sphingolipid-rich micro-domains on cell surfaces. They are generally believed to provide residency for cell surface molecules (e.g., adhesion and signaling molecules) and scaffolding to ...
Cheng Zhu +2 more
core +2 more sources
Nature Communications, 2019 Genome-wide association studies (GWAS) have identified thousands of genomic regions affecting complex diseases. The next challenge is to elucidate the causal genes and mechanisms involved.
Christopher N. Foley +6 more
semanticscholar +1 more source
A practical guide to evaluating colocalization in biological microscopy.
American Journal of Physiology - Cell Physiology, 2011 Fluorescence microscopy is one of the most powerful tools for elucidating the cellular functions of proteins and other molecules. In many cases, the function of a molecule can be inferred from its association with specific intracellular compartments or ...
K. Dunn, M. Kamocka, J. McDonald
semanticscholar +1 more source
Unsupervised Object Discovery and Localization in the Wild: Part-based Matching with Bottom-up Region Proposals [PDF]
, 2015 This paper addresses unsupervised discovery and localization of dominant objects from a noisy image collection with multiple object classes. The setting of this problem is fully unsupervised, without even image-level annotations or any assumption of a ...
Cho, Minsu +3 more
core +5 more sources