Results 91 to 100 of about 75,482 (264)

Toxic megacolon: A rare presentation and novel treatment

JPGN Reports, EarlyView.
Abstract A 14‐year‐old male presented with toxic megacolon (TM). Stool culture and rectal biopsies ruled out Clostridium difficile infection and Hirschsprung disease, respectively. Anorectal manometry ruled out anal achalasia as rectoanal inhibitory reflex elicited a normal resting pressure.
Adrienne P. Davis, Jennifer M. Schuh, Janice Bitong, Amy J. Wagner   +3 more
wiley   +1 more source

Volvulus of the Sigmoid Colon during Pregnancy: A Case Report

Case Reports in Obstetrics and Gynecology, 2012
Colonic obstruction due to sigmoid colon volvulus during pregnancy is a rare but complication with significant maternal and fetal mortality. We describe a case of sigmoid volvulus in a patient with 33 weeks of gestation that developed complete necrosis ...
Enzo Fabrício Ribeiro Nascimento, Michelle Chechter, Fábio Piovezan Fonte, Nara Puls, Juliana Santos Valenciano, Cláudio Luciano Penna Fernandes Filho, Ronaldo Nonose, Crhistiny Emmanuelle Gabriel Bonassa, Carlos Augusto Real Martinez   +8 more
doaj   +1 more source

Gastrointestinal strictures in a pediatric patient with Satoyoshi syndrome

JPGN Reports, EarlyView.
Abstract We present a novel case of gastrointestinal strictures in a young girl with Satoyoshi syndrome (SS), highlighting multi‐system features of alopecia universalis, painful muscle cramps with dystonia, aberrant growth velocity, and skeletal abnormalities.
Katherine (Tusia) Pohoreski, Gary Galante, Kiera Pajunen, Marie‐Anne Brundler, Samarjeet Bhandal, Iwona Wrobel   +5 more
wiley   +1 more source

Metachronous Sigmoid Carcinoma and Mantle Cell Lymphoma in Intestines

Case Reports in Gastroenterology, 2019
It is rare that colon carcinoma and mantle cell lymphoma (MCL) occur one after another in intestines. We found two malignancies of sigmoid carcinoma and MCL in a single patient, who had initially been diagnosed with sigmoid carcinoma and treated with ...
Qiao Yu, Qiu-Yan Liu, Dan-Ming  Wei, Dian-Zhong Luo   +3 more
doaj   +1 more source

AML‐Net: Attention‐based multi‐scale lightweight model for brain tumour segmentation in internet of medical things

CAAI Transactions on Intelligence Technology, EarlyView.
Abstract Brain tumour segmentation employing MRI images is important for disease diagnosis, monitoring, and treatment planning. Till now, many encoder‐decoder architectures have been developed for this purpose, with U‐Net being the most extensively utilised. However, these architectures require a lot of parameters to train and have a semantic gap. Some
Muhammad Zeeshan Aslam, Basit Raza, Muhammad Faheem, Aadil Raza   +3 more
wiley   +1 more source

A retrospective cohort study of the influence of lifestyle factors on survival of patients undergoing surgery for colorectal cancer. [PDF]

, 2017
Aim: Several modifiable and non-modifiable health related behaviours are associated with the incidence of Colorectal Cancer (CRC), but there is little research on their association with survival.
Anderson, Boyle, Campbell, Courneya, Courneya, Dignam, Haggar, Haydon, Holmes, Hubbard, Kuiper, Manceau, Martinez, Meyerhardt, Meyerhardt, Morrison, Oliphant, Shafique, Van Blarigan, Vartiainen, Vrieling, World Cancer Research Fund/American Institute for Cancer Research   +21 more
core   +1 more source

Five‐year outcome of laparoscopic transanal total mesorectal excision in a single centre—A training model to acquire a new surgical technique

Surgical Practice, EarlyView.
Abstract Background Laparoscopic transanal total mesorectal excision (TaTME) has been widely adopted globally. Short‐ and long‐term outcomes vary across different localities, especially during the learning phase. Method and patient The first 100 cases of TaTME performed by two experienced colorectal surgeons between 2015 and 2019 were reviewed. The aim
Sophie Sok Fei Hon, Janet Fung Yee Lee, Julie Hoi Yan Ng, Kaori Futaba, Simon Chu, Simon Siu Man Ng   +5 more
wiley   +1 more source

Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition [PDF]

, 2016
EZH2 inhibitors have gained great interest for their use as anti-cancer therapeutics. However, most research has focused on EZH2 mutant cancers and recently adverse effects of EZH2 inactivation have come to light.
Bounova, Gergana, Cornelissen-Steijger, Paulien, de Vries, Nienke, Koppens, Martijn A.J., Sansom, Owen J., van Lohuizen, Maarten, Wessels, Lodewyk F.A.   +6 more
core   +1 more source

Understanding and Addressing Clinical Variation in Rectal Cancer Care: Application of an Analytic Framework

Asia-Pacific Journal of Clinical Oncology, EarlyView.
There is substantial clinical variation in the use of neoadjuvant radiotherapy for high‐risk rectal cancer, ranging from 25% to 59% in New South Wales, Australia. Assessed against an empirically based analytic framework, the reasons for this clinical variation were largely unwarranted and related to MDT processes, imaging quality, workforce/practice ...
Bernadette (Bea) Brown, Daniel Steffens, Michael Solomon, Cherry Koh, Jane Young   +4 more
wiley   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source