Results 91 to 100 of about 1,035,049 (315)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Evalution of the Patients with Colon Polyps in Terms of Helicobacter pylori with Sydney Criteria

, 2019
Aim:Colorectal cancer (CRC) is one of the leading three cancers with high mortality. Colon polyps are precursors for CRC development. Helicobacter pylori is known to increase the risk of gastric cancer by intestinal metaplasia (IM) and glandular atrophy (
Özlem Özdemir, Çağrı Akalın
core   +1 more source

Role of intersticial cells of Cajal in the pacemaker activity and neurotransmission in the rat colon [PDF]

, 2005
Consultable des del TDXTítol obtingut de la portada digitalitzadaEls objectius d'aquesta tesi han estat l'estudi de la funció de les cèl·lules intersticials de Cajal (ICCs) en l'activitat marcapassos i en la transmissió neuromuscular, dins el tracte ...
Albertí i Martínez de Velasco, Elena
core   +1 more source

Metformin’s impact on tumor regression grade in diabetic patients with rectal cancer undergoing neoadjuvant chemoradiotherapy

Scientific Reports
This retrospective study was designed to investigate the impact of metformin use on the efficacy of neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer. It is a retrospective, single institution study.
Nai-Yu Lin, Kun-Yu Tsai, Yen-Lin Huang, Bor-Kang Jong, Zhen-Hao Yu, Ching-Chung Cheng, Shu-Huan Huang, Jeng-Fu You, I-Li Lai   +8 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Endogenous N-nitroso compounds, and their precursors, present in bacon, do not initiate or promote aberrant crypt foci in the colon of rats [PDF]

, 2000
Processed meat intake is associated with increased risk of colorectal cancer. This association may be explained by the endogenous formation of N-nitroso compounds (NOC).
Peiffer, Ginette, Pignatelli, Brigitte, Parnaud, Géraldine, Taché, Sylviane, Corpet, Denis E.   +4 more
core  

The omnivorous Tyrolean Iceman: colon contents (meat, cereals, pollen, moss and whipworm) and stable isotope analyses [PDF]

, 2000
The contents of the colon of the Tyrolean Iceman who lived Ga. 5300 years ago include muscle fibres, cereal remains, a diversity of pollen, and most notably that of the hop hornbeam (Ostrya carpinifolia) retaining cellular contents, as well as a moss ...
Preston, T., Dickson, J.H., Holden, T.G., Handley, L.L., O'Connell, T.C., Oeggl, K.   +5 more
core   +1 more source

An unusual case of proctosigmoiditis secondary to arteriovenous fistulization

The Turkish Journal of Gastroenterology, 2017
Refractory chronic colitis presents a medical and surgical challenge, and underlying etiologies are diverse with potential for misclassification as inflammatory bowel disease.
Veljko Strjina, Scott R. Kelley
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source