Results 91 to 100 of about 1,488,963 (303)

Calculation of the thermodynamic properties of a mixture of gases as a function of temperature and pressure [PDF]

The evaluation of the thermodynamic properties of a gas mixture can be performed using a generalized correlation which makes use of the second virial coefficient.
Colon, G.
core   +1 more source

The continuity of the inversion and the structure of maximal subgroups in countably compact topological semigroups

, 2009
In this paper we search for conditions on a countably compact (pseudo-compact) topological semigroup under which: (i) each maximal subgroup $H(e)$ in $S$ is a (closed) topological subgroup in $S$; (ii) the Clifford part $H(S)$(i.e.
A. B. Paalman-de-Miranda, B. Bokalo, C. Eberhart, D. Pagon, D. Repovš, J. A. Hildebrant, J. H. Carruth, K. Numakura, N. Brand, O. Gutik, O. Gutik, P. Koszmider, P. S. Kenderov, R. E. Madariaga-Garcia, R. Ellis, S. P. Franklin, T. Banakh, T. O. Banakh   +17 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Metformin’s impact on tumor regression grade in diabetic patients with rectal cancer undergoing neoadjuvant chemoradiotherapy

Scientific Reports
This retrospective study was designed to investigate the impact of metformin use on the efficacy of neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer. It is a retrospective, single institution study.
Nai-Yu Lin, Kun-Yu Tsai, Yen-Lin Huang, Bor-Kang Jong, Zhen-Hao Yu, Ching-Chung Cheng, Shu-Huan Huang, Jeng-Fu You, I-Li Lai   +8 more
doaj   +1 more source

Colonic Mucormycosis [PDF]

American Journal of Gastroenterology, 2012
S, Rodrigues, L, Santos, J, Nuak, J, Pardal, J A, Sarmento, G, Macedo   +5 more
openaire   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

An unusual case of proctosigmoiditis secondary to arteriovenous fistulization

The Turkish Journal of Gastroenterology, 2017
Refractory chronic colitis presents a medical and surgical challenge, and underlying etiologies are diverse with potential for misclassification as inflammatory bowel disease.
Veljko Strjina, Scott R. Kelley
doaj   +1 more source