Results 101 to 110 of about 1,052,853 (316)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Validation of a novel imaging-guided and anatomy-based classification system for anorectal fistulas: a retrospective clinical evaluation study [PDF]

Annals of Coloproctology
Purpose This study was conducted to evaluate the validity of a new imaging-guided, anatomy-based classification of anorectal fistulas in defining disease severity and predicting surgical outcomes.
Antonio Brillantino, Francesca Iacobellis, Luigi Marano, Adolfo Renzi, Pasquale Talento, Luigi Brusciano, Claudio Gambardella, Umberto Favetta, Michele Schiano Di Visconte, Luigi Monaco, Maurizio Grillo, Mauro Natale Maglio, Fabrizio Foroni, Alessio Palumbo, Maria Laura Sandoval Sotelo, Luciano Vicenzo, Elisa Palladino, Giovanna Frezza, Maria Paola Menna, Paolino Mauro, Stefano Picardi, Mario Massimo Mensorio, Vinicio Mosca, Vincenzo Bottino, Giovanna Ioia, Corrado Rispoli, Marco Di Serafino, Martina Caruso, Roberto Ronza, Barbara Frittoli, Daria Schettini, Luca Stoppino, Franco Iafrate, Giulio Lombardi, Carmine Antropoli, Salvatore Cappabianca, Ludovico Docimo, Roberto Grassi, Alfonso Reginelli   +38 more
doaj   +1 more source

Applying toponome imaging system for studying colon cancer [PDF]

Introduction In a proof of principle study, we have applied an automated fluorescence toponome imaging system (TIS) in order to examine, whether TIS can find protein network structures distinguishing cancerous from normal colon tissue from same ...
Bhattacharya, Sayantan
core  

Hyperspectral colon tissue cell classification [PDF]

, 2004
A novel algorithm to discriminate between normal and malignant tissue cells of the human colon is presented. The microscopic level images of human colon tissue cells were acquired using hyperspectral imaging technology at contiguous wavelength intervals ...
Rajpoot, Nasir M. (Nasir Mahmood), Turner, Martin J., Rajpoot, Kashif   +2 more
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

An unusual case of proctosigmoiditis secondary to arteriovenous fistulization

The Turkish Journal of Gastroenterology, 2017
Refractory chronic colitis presents a medical and surgical challenge, and underlying etiologies are diverse with potential for misclassification as inflammatory bowel disease.
Veljko Strjina, Scott R. Kelley
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Predictors for temporary stomas non-closure among non-metastatic rectal cancer patients undergoing curative resection: a retrospective analysis

World Journal of Surgical Oncology
Background The primary treatment for non-metastatic rectal cancer is curative resection. However, sphincter-preserving surgery may lead to complications.
Chia-Chien Hsu, Wen-Sy Tsai, Tzong-yun Tsai, Jeng-Fu You, Chien-Yuh Yeh, Pao-Shiu Hsieh, Reiping Tang, Shu-Huan Huang   +7 more
doaj   +1 more source

Gastrointestinal stromal tumors (GIST) of the anus: A single institution experience

The Turkish Journal of Gastroenterology, 2019
Cite this article as: Scow JS, Mathis KL. Gastrointestinal stromal tumors (GIST) of the anus: A single institution experience.
Jeffrey S. Scow, Kellie L. Mathis
doaj   +1 more source