Results 81 to 90 of about 1,052,853 (316)

Squamous Cell Carcinoma Originating from a Crohn’s Enterocutaneous Fistula

Case Reports in Surgery, 2017
Purpose. Squamous cell carcinoma (SCC) developing within fistulae and chronic wounds in patients with Crohn’s disease is a rare phenomenon with few reported studies in the literature.
Bogdan Protyniak, Travis Shutt, Russell Farmer   +2 more
doaj   +1 more source

Familial Associations of Colon and Rectal Cancers With Other Cancers

, 2019
BACKGROUND: Many studies have indicated that colon and rectal cancers differ in etiology and histology. OBJECTIVE: The aim of this study was to investigate whether the associations of colon and rectal cancers with any other (discordant) cancer were site ...
Hemminki, Akseli,, Yu, Hongyao,, Hemminki, Kari,, Sundquist, Kristina,, Lund University.   +4 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men [PDF]

, 2005
Tumours in rodent and human colon share many histological and genetic features. To know if rodent models of colon carcinogenesis are good predictors of chemopreventive efficacy in humans, we made a meta-analysis of aspirin, beta-carotene, calcium, and ...
Denis E. Corpet, Pierre, Fabrice, Pierre, Fabrice H.F., Fabrice Pierre, Corpet, Denis E.   +4 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Effect of autonomic nervous system resection extent on urinary dysfunction in robotic rectal cancer surgery

Annals of Gastroenterological Surgery
Aim We investigated whether autonomic nervous system resection during robotic rectal surgery contributes to urinary dysfunction and to what extent. Methods This retrospective cohort study included patients who underwent rectal surgery for primary rectal ...
Sodai Arai, Hiroyasu Kagawa, Akio Shiomi, Yusuke Yamaoka, Shoichi Manabe, Chikara Maeda, Yusuke Tanaka, Shunsuke Kasai, Akifumi Notsu, Yusuke Kinugasa   +9 more
doaj   +1 more source

FISTULA OF THE COLON

Annals of Surgery, 1918
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openaire   +4 more sources

Colon Crypt Model 031215.nlogo

, 2015
Computer program that simulates human colon cancer initiation, therapy, and prevention. Includes interface, code, and detailed information. Useful for in silico experiments directly from the user interface. Illustrates and plots the cell dynamics of stem
Axelrod, David E.
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Postoperative Survival Analysis of Elective Colorectal Cancer Surgery with Liver Cirrhosis: A Propensity-Matched Study

Current Oncology
Background: Liver cirrhosis increases perioperative risk in colorectal cancer surgery, yet data on long-term outcomes remain limited. In this study, we evaluated postoperative morbidity, mortality, and survival in cirrhotic patients.
Tsung-Jung Tsai, Kai-Jyun Syu, Xuan-Yuan Huang, Yu Shih Liu, Chang-Wei Chen, Yu-Yao Chang, Yen-Hang Wu, Tsung Chuang   +7 more
doaj   +1 more source