Results 61 to 70 of about 1,035,049 (315)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Glycemic index, nutrient density, and promotion of aberrant crypt foci in rat colon [PDF]
, 1998 We speculated that a diet with a high glycemic index (GI), or a diet with a low nutrient density (nutrient-to-calorie ratio), would enhance colon carcinogenesis, presuma-bly via increased insulin resistance.
Peiffer, Ginette +2 more
core
Annals of Gastroenterological SurgeryBackground This study aimed to evaluate the clinical utility and prognostic significance of sarcopenia classification based on the psoas major muscle volume index (PVI) in elderly patients with rectal cancer.
Gen Tsujio +8 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Spatial analysis for colon biopsy classification from hyperspectral imagery [PDF]
, 2008 Automatic classification of histology images, the objective of our research, is aimed at supporting the pathologists in their diagnosis. In this paper, we present a comparative study between 3D spectral/spatial analysis (SSA) and 2D spatial analysis (SA ...
Rajpoot, Nasir M. (Nasir Mahmood) +1 more
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Colon Crypt Model 031215.nlogo
, 2015 Computer program that simulates human colon cancer initiation, therapy, and prevention. Includes interface, code, and detailed information. Useful for in silico experiments directly from the user interface. Illustrates and plots the cell dynamics of stem
Axelrod, David E.
core +1 more source
Wideband Transimpedance Amplifiers for Optoelectronics: Applications to Dynamic Interferometry
Revista Elektrón, 2017 —This paper describes the design and performance of transimpedance amplifiers (TIAs) for optoelectronic systems, optimized for optical dynamic interferometry.
Lucas Matías Riobó +3 more
doaj
Annals of Gastroenterological SurgeryAim Few reports have described pelvic reinforcement procedure (PRP) to prevent perineal hernia (PH) in robotic abdominoperineal resection (Ro‐APR) for rectal cancer. This study aimed to investigate the safety and efficacy of PRP in Ro‐APR.
Yoshihiro Sakai +8 more
doaj +1 more source
Amoeboma of colon mimicking colonic carcinoma
Tropical Parasitology, 2014 Entamoeba histolytica is a major cause of diarrhea in the developing countries and it can present with a wide range of gastrointestinal symptoms depending on the phase of the infection. We describe a case of 65-year-old male patient presented with abdominal pain and vomiting. On the clinical and radiological examination provisional diagnosis of colonic
Saha, Kaushik +3 more
openaire +3 more sources