Results 41 to 50 of about 1,052,853 (316)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Case Reports in SurgeryBuschke-Löwenstein tumor (BLT) is a rare, locally aggressive anogenital tumor associated predominantly with low-risk human papillomavirus (HPV) types 6 and 11.
Sabrina E. Chin +2 more
doaj +1 more source
Is preoperative chemoradiotherapy warranted in magnetic resonance imaging-based clinically T3N0 rectal cancer? [PDF]
Korean Journal of Clinical Oncology, 2014 Purpose: Preoperative chemoradiotherapy (PCRT) has been widely adopted. However, benefit of PCRT for patients with clinically T3N0 (cT3N0) rectal cancer is doubtful.
Jee Yeon Kim +7 more
doaj +1 more source
Colonic Protein Fermentation and Promotion of Colon Carcinogenesis by Thermolyzed Casein [PDF]
, 1995 Thermolyzed casein is known to promote the growth of aberrant crypt foci (ACF) and colon cancer when it is fed to rats that have been initiated with azoxymethane.
Thompson, Lilian +5 more
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Protective loop ileostomy or colostomy? A risk evaluation of all common complications [PDF]
Annals of ColoproctologyPurpose Protective ileostomy and colostomy are performed in patients undergoing low anterior resection with a high leakage risk. We aimed to compare surgical, medical, and daily care complications between these 2 ostomies in order to make individual ...
Yi-Wen Yang +8 more
doaj +1 more source
Colon capsule endoscopy for colonic surveillance [PDF]
Colorectal Disease, 2019 AbstractAimResources used in surveillance colonoscopies are taking up an increasing proportion of colonoscopy capacity. Colon capsule endoscopy (CCE) is a promising technique for noninvasive investigation of the colon. We aimed to investigate CCE as a possible filter in colonic surveillance with the primary outcome of reducing the number of ...
Kroijer, R. +4 more
openaire +2 more sources
Hyperspectral texture analysis for colon tissue biopsy classification [PDF]
, 2007 Diagnosis and cure of colon cancer can be improved by performing automated histopathological analysis of colon biopsy samples. Due to significant observational variation between pathologists in several histological features, there is a need for the ...
Rajpoot, Nasir M. (Nasir Mahmood) +3 more
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
World Journal of Surgical Oncology, 2019 Background Local excision (LE) is a feasible treatment approach for rectal cancers in stage pT1 and presents low pathological risk, whereas total mesorectal excision (TME) is a reasonable treatment for more advanced cancers. On the basis of the pathology
I-Li Lai +12 more
doaj +1 more source