Results 131 to 140 of about 207,764 (268)

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Colonic Mucormycosis [PDF]

American Journal of Gastroenterology, 2012
S, Rodrigues, L, Santos, J, Nuak, J, Pardal, J A, Sarmento, G, Macedo   +5 more
openaire   +2 more sources

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

Impact of resection for ovarian metastases from colorectal cancer and clinicopathologic analysis: A multicenter retrospective study in Japan

Annals of Gastroenterological Surgery
Aim The aim of this study was to clarify the significance of resection of ovarian metastases from colorectal cancer and to identify the clinicopathologic characteristics.
Hiroyasu Kagawa, Yusuke Kinugasa, Tomohiro Yamaguchi, Masayuki Ohue, Kazushige Kawai, Junichiro Hiro, Seiichi Shinji, Hiroaki Nozawa, Yasumitsu Hirano, Koji Komori, Yasumasa Takii, Takeshi Suto, Shunsuke Tsukamoto, Yoshito Akagi, Heita Ozawa, Yuji Toiyama, Kazuhito Minami, Tomoharu Shimizu, Kay Uehara, Kazuhiro Sakamoto, Keita Mori, Kenichi Sugihara, Yoichi Ajioka   +22 more
doaj   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Role of intersticial cells of Cajal in the pacemaker activity and neurotransmission in the rat colon

, 2005
Consultable des del TDXTítol obtingut de la portada digitalitzadaEls objectius d'aquesta tesi han estat l'estudi de la funció de les cèl·lules intersticials de Cajal (ICCs) en l'activitat marcapassos i en la transmissió neuromuscular, dins el tracte ...
Albertí i Martínez de Velasco, Elena
core  

Robotic Approach to Colon Resection

, 2016
Robotic surgical techniques are being increasingly adopted as a tool in the minimally invasive armamentarium of the colorectal surgeon. These platforms present numerous potential advantages in visualization, precise dissection, and tissue manipulation ...
Francone, Todd D., Waters, Joshua A.
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Functional results after ventral mesh rectopexy in 50 patients with obstructed defecation and/or fecal incontinence

Revista de Gastroenterología de México (English Edition)
Introduction and aim: Ventral mesh rectopexy (VMR) for correcting rectal prolapse, rectocele, and enterocele improves obstructed defecation syndrome (ODS) and fecal incontinence (FI).
A. Rivera-Garcia Granados, M.A. López-Ramírez, F. Urbina-Alatriste, V. Flores-Gamboa   +3 more
doaj   +1 more source