Results 161 to 170 of about 1,737,210 (406)

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Short Chain Fatty Acids in the Colon and Peripheral Tissues: A Focus on Butyrate, Colon Cancer, Obesity and Insulin Resistance

Nutrients, 2017
Increased dietary fiber consumption has been associated with many beneficial effects, including amelioration of obesity and insulin resistance. These effects may be due to the increased production of short chain fatty acids, including propionate, acetate
Sean M. McNabney, T. Henagan
semanticscholar   +1 more source

HQColon: A Hybrid Interactive Machine Learning Pipeline for High Quality Colon Labeling and Segmentation [PDF]

arXiv
High-resolution colon segmentation is crucial for clinical and research applications, such as digital twins and personalized medicine. However, the leading open-source abdominal segmentation tool, TotalSegmentator, struggles with accuracy for the colon, which has a complex and variable shape, requiring time-intensive labeling.
arxiv  

On the Frobenius functor and colon ideals [PDF]

arXiv, 2007
In this paper we study the commutativity of the Frobenius functor and the colon operation of two ideals for Noetherian rings of positive characteristic $p$. New characterizations of regular rings and local UFDs are given.
arxiv  

Predictors for temporary stomas non-closure among non-metastatic rectal cancer patients undergoing curative resection: a retrospective analysis

World Journal of Surgical Oncology
Background The primary treatment for non-metastatic rectal cancer is curative resection. However, sphincter-preserving surgery may lead to complications.
Chia-Chien Hsu, Wen-Sy Tsai, Tzong-yun Tsai, Jeng-Fu You, Chien-Yuh Yeh, Pao-Shiu Hsieh, Reiping Tang, Shu-Huan Huang   +7 more
doaj   +1 more source

PHYSIOLOGY OF THE COLON, SIGMOID AND RECTUM. [PDF]

, 1898
J. G. CARPENTER
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

ACLY facilitates colon cancer cell metastasis by CTNNB1

Journal of experimental & clinical cancer research : CR, 2019
Colon cancer is the second leading cancer worldwide. Recurrent disease and chemotherapeutic drug resistance are very common in the advanced stage of colon cancer.
Jun Wen, Xuejie Min, Mengqin Shen, Qian Hua, Yuan Han, Li Zhao, Liu Liu, Gang Huang, Jianju Liu, Xiaoping Zhao   +9 more
semanticscholar   +1 more source

A priori mixed hadrons, hyperon non-leptonic decays, and the |\Delta I|=1/2 rule

, 2001
The |\Delta I|=1/2 rule in non-leptonic decays of hyperons can be naturally understood by postulating a priori mixed physical hadrons, along with the isospin invariance of the responsible transition operator.
Garcia, A., Huerta, R., Sanchez-Colon, G.   +2 more
core   +1 more source

Transitivity of some uniformities on fuzzy sets [PDF]

arXiv
Given a uniform space $(X, \mathcal{U})$, we denote by $\mathcal{F}(X)$ to the family of all normal upper semicontinuous fuzzy sets $u \colon X \to [0,1]$ with compact support. In this paper, we study transitivity on some uniformities on $\mathcal{F}(X)$: the level-wise uniformity $\mathcal{U}_{\infty}$, the Skorokhod uniformity $\mathcal{U}_{0}$, and ...
arxiv