Results 171 to 180 of about 1,052,853 (316)

Il carcinoma del colon retto metastatico- Sicurezza ed efficiacia di Panitumumab dopo reazioni infusionali da Cetuximab nel carcinoma del colon retto metastatico

, 2012
Raccolta casi clinici sul tumore del colon retto ...
DE LUCA, CRISTINA, LO RUSSO, VALENTINA, GIOVANNONI, SARA, Iolanda Speranza, DI SERI, Marisa   +4 more
core  

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Medullary adenocarcinoma of the ascending colon mimicking appendicitis after prior appendectomy. [PDF]

J Surg Case Rep
Cummings-Ruiz IL, Nieves-Munoz JO, Acevedo S, Bolaños Avila GE.   +3 more
europepmc   +1 more source

Vimentin neutralizing antibody ameliorate inflammatory bowel disease by inhibiting fibrosis and inflammatory cell death. [PDF]

PLoS One
Kim S, Kang HY, Park JS, Choi J, Jeong HY, Lee SY, Lee HH, Lee BI, Cho ML.   +8 more
europepmc   +1 more source

Perforazione retroperitoneale della malattia diverticolare del colon

, 1989
A series of 29 cases of diverticulosis of the colon observed from 1970 to date, are reported. An interesting case is illustrated.
CARCOFORO, Paolo, ZANDI, Giuseppe, RUBBINI, Michele, R. Marzola, G. Vettorello, ANANIA, Gabriele, MASCOLI, Francesco, T. Virgili, GASBARRO, Vincenzo   +8 more
core  

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

A Case of Diversion Colitis Successfully Treated by Synbiotic Stimulation via the Efferent Limb. [PDF]

Case Rep Surg
Tsubokawa Y, Nishida K, Kato T.
europepmc   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

Advanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen, Yuan Cheng, Liang Cheng   +11 more
wiley   +1 more source

One patient with synchronous multiple primary colon cancers which is easy to miss: a case report. [PDF]

Front Surg
Bao X, Liu H, Wu M, Liu X.
europepmc   +1 more source

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source