Results 11 to 20 of about 1,279,401 (299)

Permanent stoma: a quality outcome in treatment of rectal cancer and its impact on length of stay

open access: yesBMC Surgery, 2021
Background This study aimed to identify socioeconomic predictors of permanent stoma in rectal cancer treatment and examine its association with length of stay at the treatment facility.
Riccardo Lemini   +6 more
doaj   +1 more source

Comprehensive molecular characterization of human colon and rectal cancer

open access: yesNature, 2012
To characterize somatic alterations in colorectal carcinoma, we conducted a genome-scale analysis of 276 samples, analysing exome sequence, DNA copy number, promoter methylation and messenger RNA and microRNA expression.
D. Muzny   +312 more
semanticscholar   +1 more source

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Anorectal Abscess, Fistula-in-Ano, and Rectovaginal Fistula.

open access: yesDiseases of the Colon & Rectum, 2022
On behalf of the Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons 1 Division of Colon and Rectal Surgery, University of Minnesota, Minneapolis, Minnesota 2 Department of Surgery, Uniformed Services University of
W. Gaertner   +8 more
semanticscholar   +1 more source

Prognostic value of the C-reactive protein to albumin ratio in colorectal cancer: an updated systematic review and meta-analysis

open access: yesWorld Journal of Surgical Oncology, 2021
Backgrounds The inflammatory biomarker “C-reactive protein to albumin ratio (CAR)” has been reported to significantly correlate to a variety of human cancers.
Chun-Kai Liao   +6 more
doaj   +1 more source

Normalization of Real-Time Quantitative Reverse Transcription-PCR Data: A Model-Based Variance Estimation Approach to Identify Genes Suited for Normalization, Applied to Bladder and Colon Cancer Data Sets

open access: yesCancer Research, 2004
Accurate normalization is an absolute prerequisite for correct measurement of gene expression. For quantitative real-time reverse transcription-PCR (RT-PCR), the most commonly used normalization strategy involves standardization to a single ...
C. Andersen, J. L. Jensen, T. Ørntoft
semanticscholar   +1 more source

Predictive biomarkers of colon cancer immunotherapy: Present and future

open access: yesFrontiers in Immunology, 2022
Immunotherapy has revolutionized colon cancer treatment. Immune checkpoint inhibitors (ICIs) have shown clinical benefits for colon cancer patients, especially those with high microsatellite instability (MSI-H).
Wanting Hou, C. Yi, Hong Zhu
semanticscholar   +1 more source

Risk factors for delayed perineal wound healing and its impact on prolonged hospital stay after abdominoperineal resection

open access: yesWorld Journal of Surgical Oncology, 2019
Background Perineal wound complications are a long-lasting issue for abdominoperineal resection (APR) patients. Complication rates as high as 60% have been reported, with the most common complication being delayed perineal wound healing.
Chu-Cheng Chang   +10 more
doaj   +1 more source

Preventing parastomal hernias with systematic intraperitoneal specifically designed mesh

open access: yesBMC Surgery, 2017
Background Parastomal hernia is a very common complication after stoma formation. Current surgical techniques for repairing parastomal hernia have unsatisfactory results. We aim to assess our preliminary experience with prophylactic mesh placement at the
Raquel Conde-Muíño   +5 more
doaj   +1 more source

Differences in gene mutations according to gender among patients with colorectal cancer

open access: yesWorld Journal of Surgical Oncology, 2018
Background The incidence, site distribution, and mortality rates of patients with colorectal cancer differ according to gender. We investigated gene mutations in colorectal patients and wanted to examine gender-specific differences.
Yi-Jian Tsai   +11 more
doaj   +1 more source

Metformin increases pathological responses to rectal cancers with neoadjuvant chemoradiotherapy: a systematic review and meta-analysis

open access: yesWorld Journal of Surgical Oncology, 2023
Background To summarize the chemo-radio effect of metformin in rectal cancers with neoadjuvant chemoradiotherapy on pathological response, tumor regression grade (TRG), and T/N downstaging.
I-Li Lai   +5 more
doaj   +1 more source

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