Results 201 to 210 of about 1,279,401 (299)

CFTR Cl− channel function in native human colon correlates with the genotype and phenotype in cystic fibrosis [PDF]

open access: bronze, 2004
Stephanie Hirtz   +14 more
openalex   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

open access: yesAdvanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai   +12 more
wiley   +1 more source

Primary leiomyosarcoma of the descending colon initially non-diagnostic on biopsy: a case report. [PDF]

open access: yesWorld J Surg Oncol
Pyo DH   +6 more
europepmc   +1 more source

Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer [PDF]

open access: gold, 2017
Sebastian Lamprecht   +6 more
openalex   +1 more source

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

open access: yesAdvanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu   +7 more
wiley   +1 more source

Spontaneous colonic perforation in a pediatric patient with acute febrile illness: a case report. [PDF]

open access: yesJ Surg Case Rep
Yadav A   +5 more
europepmc   +1 more source

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

open access: yesAdvanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai   +13 more
wiley   +1 more source

Response to Comment on A Method for Continuous Surgeon Improvement in Rectal Cancer

open access: yesAnnals of Surgery Open
Davide Ferrari, MD   +5 more
doaj   +1 more source

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