Results 241 to 250 of about 5,799,531 (403)

Automating tumor-stroma ratio quantification in colon cancer patients from the UNITED study. [PDF]

ESMO Open
Heilijgers F, Polack M, Roodvoets AGH, Meershoek-Klein Kranenbarg E, Peeters KCMJ, Buettner R, Tolkach Y, Mesker WE, UNITED Collaboration.   +8 more
europepmc   +1 more source

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source

Colorectal Cancer Screening Using Flexible Sigmoidoscopy: United Kingdom Study Demonstrates Significant Incidence and Mortality Benefit

Canadian Journal of Gastroenterology, 2010
Robert J Hilsden, Alaa Rostom
doaj   +1 more source

Hematological markers as prognostic predictors in patients undergoing colon cancer surgery. [PDF]

Sci Rep
Gonzales Stuva JP, Pérez-López C, Ramírez Romero MS, Bernabeu García A, Vivas Angeles P, Escolà Ripoll D, López Gordo S.   +6 more
europepmc   +1 more source

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

Advanced Science, EarlyView.
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik, Christopher J. Ward, Soura Chakraborty, Ziwei Zhang, Daniel Heraghty, Prasanna Suresh, Bing Li, Shekhar Kedia, Jhuma Pramanik, Simon J. Davis, James P. Roy, Michael A. Chapman, Bidesh Mahata, David Klenerman   +13 more
wiley   +1 more source

<i>XPO5</i> Polymorphism in Colon Cancer Patients: A Cross-Sectional Study. [PDF]

Int J Mol Sci
Agbektas T, Genc HC, Zontul C, Tas A.
europepmc   +1 more source

Network pharmacology and bioinformatics analysis identify potential therapeutic effects of berberine on colon cancer complicated with radiation enteritis

Ziqiao Yan, Hongyang Yu, Liangliang Zhang, Zebin Liao, Xiangwei Ge, Yuguo Wang, Peiyu Tian, Zhexin Ni, Yongqi Dou, Yue Gao   +9 more
openalex   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

Screening of healthcare staff for the prevention of colon cancer. [PDF]

Prz Gastroenterol
Peteinaris A, Mulita F, Bekou E, Lakiotaki D, Kostopoulou IE, Liolis E, Tatanis V, Tasios K, Tchabashvili L, Antzoulas A, Garantzioti V, Koutras A, Spinos T, Mylonopoulou M, Bouchagier K, Schizas D.   +15 more
europepmc   +1 more source

Rapidly Progressive Fatal Gas Gangrene due to Clostridium Septicum in a Patient with Colon Cancer Revealed by Autopsy [PDF]

, 2017
Kuno Haruka, Harumi Gomi, Kazutaka Fukushima, Yukiko Kodama, Taijiro Shirokawa, Miura Kousei, Shijima Taguchi, Norio Takayashiki, Kanai Takao   +8 more
openalex   +1 more source