Results 41 to 50 of about 1,403,065 (291)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Diaspora: (post)colonial visions [PDF]

open access: yes, 2014
The exhibition 'Diaspora: (Post)colonial Visions’ is part of the project ‘Memory Matters’, a partnership between the School of Social Policy, Sociology and Social Research (University of Kent) and CORECOG, a Congolese community group based in East London.
Garbin, David
core  

Tensions of colonial punishment: perspectives on recent developments in the study of coercive networks in Asia, Africa and the Caribbean [PDF]

open access: yes, 2000
The study of penal practices in colonised parts of Asia, Africa, Latin America, the Indian Ocean and the Caribbean has recently witnessed a significant shift.
Altink   +77 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Génesis, evolución y universalidad de los derechos humanos ante la diversidad de las culturas

open access: yesEstudios de Asia y África, 1997
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Étienne-Richard Mbaya   +1 more
doaj  

Settler colonialism, multiculturalism and the politics of postcolonial identity [PDF]

open access: yes, 2015
The twentieth century saw the development of nationalism and the construction of postcolonial identities in many newly independent nations. Formerly colonised peoples have struggled to restore and adapt their customs and to construct postcolonial ...
Lovell, Melissa
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

May it Please Your Honor : Letters of Petition as Historical Evidence in an African Colonial Context [PDF]

open access: yes, 2010
This paper presents some preliminary conclusions drawn from an ongoing project which aims to collect and collate letters of petitions in colonial Nigeria as primary source for historians and other scholars.
Korieh, Chima J.
core   +1 more source

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