Results 71 to 80 of about 79,968 (214)
The expansion of England? Scotland, architectural history, and the wider British world [PDF]
Journal of Art Historiography, 2018 This article makes a case for both recognizing and understanding the unique Scottish contribution to the history of architecture in the British colonial world.
G.A. Bremner
doaj
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Sentencia y penitencia: caminos hacia la reconciliación en la sociedad colonial
Fronteras de la Historia, 1997 En el siglo XVI Felipe II creó el Tribunal de la Inquisición de Lima cuya jurisdicción era continental. Tal amplitud jurisdiccional hizo que fuera incapaz de atender debidamente todos los casos de su competencia.
Luis Enrique Rodríguez Baquero
doaj
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Fronteras de la HistoriaEn los años posteriores a la fundación del obispado de Santa María la Antigua, la Corona española buscó extender la presencia de la Iglesia a otros espacios de Tierra Firme, tanto al este como al oeste del istmo de Panamá.
Jimena Guerrero Ramírez
doaj
Pulperos rurales: entre la vida privada y la pública
Mundo Agrario, 2004 Este trabajo estudia la vida privada del pulpero rural de la campaña de Buenos Aires y las actividades que desarrolla cuando no se encuentra frente a su negocio.
Julián Carrera
doaj
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source