Results 131 to 140 of about 90,261 (311)

Magnetic resonance imaging of colonic function [PDF]

, 2011
The overall aim of this work was to develop MRI methods and techniques to study the physiology and the pathology of the gastrointestinal tract, with particular attention to the colon.
Placidi, Elisa
core  

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Human psychophysiological responses to visceral and somatic pain – the development of integrated, reproducible human pain phenotypes

, 2011
PhDBackground Pain is the ubiquitous human experience, yet displays considerable inter- and intraindividual variability in health and disease. Many factors have been proposed to account for these differences.
Farmer, Adam Donald
core  

Up-Regulation of Annexin-A1 and Lipoxin A(4) in Individuals with Ulcerative Colitis May Promote Mucosal Homeostasis

, 2012
PubMed ID: 22723974This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Jose G P Ferraz, Linda Vong, Panaccione, R, Panaccione Remo, Philip M. Sherman, Philip M Sherman, Perretti, M, Beck Paul L., Ferraz, JGP, Sherman Philip M., John L. Wallace, Vong Linda, Sherman, PM, Wallace John L., Mauro Perretti, Jose G. P. Ferraz, Paul L. Beck, Neil Dufton, Remo Panaccione, Dufton, N, Ferraz Jose G. P., Beck, PL, Dufton Neil, Wallace, JL, Vong, L, John L Wallace, Perretti Mauro, Paul L Beck   +27 more
core   +1 more source

Targeted expression of the immunomodulatory peptide Scy by engineered Escherichia coli Nissle 1917 for alleviating enterotoxigenic E. coli infection

Frontiers in Immunology
Oral delivery of functional small peptides holds great promise for the prevention and treatment of intestinal diseases. However, their clinical application is limited by rapid degradation in the gastrointestinal tract, low bioavailability, and poor ...
Jie Fu, Jie Fu, Jie Fu, Jie Fu, Lutong Zhou, Lutong Zhou, Lutong Zhou, Xiao Jiang, Xiao Jiang, Xiao Jiang, Hong Zhang, Hong Zhang, Hong Zhang, Yanli Chen, Yanli Chen, Yanli Chen, Lei Qiao, Lei Qiao, Lei Qiao, Deguang Song, Zeqing Lu, Zeqing Lu, Zeqing Lu, Tenghao Wang, Mingliang Jin, Mingliang Jin, Mingliang Jin, Caiqiao Zhang, Yizhen Wang, Yizhen Wang, Yizhen Wang, Yuanzhi Cheng, Yuanzhi Cheng, Yuanzhi Cheng   +33 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

Advanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang, Rui Chen, Yu Chen, Haowen Lu, Yuchen Qian, Zhiheng Gao, Zheming Shen, Xiaofei Zheng, Huilin Yang, Jun Zou, Yusen Qiao   +10 more
wiley   +1 more source

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

Advanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto, Manuel Alejandro Vazquez Valle, Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Iván Velasco, Genaro Vázquez‐Victorio, Itzel Escobedo‐Avila   +6 more
wiley   +1 more source

IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancer

Nature Communications
Enteric glia have been recently recognized as key components of the colonic tumor microenvironment indicating their potential role in colorectal cancer pathogenesis.
Lies van Baarle, Veronica De Simone, Linda Schneider, Sneha Santhosh, Saeed Abdurahiman, Francesca Biscu, Reiner Schneider, Lisa Zanoletti, Renata Siqueira de Mello, Sara Verbandt, Zedong Hu, Michelle Stakenborg, Bo-Jun Ke, Nathalie Stakenborg, Raquel Salvador Laureano, Balbina García-Reyes, Jonas Henn, Marieta Toma, Maxime Vanmechelen, Guy Boeckxstaens, Frederik De Smet, Abhishek D. Garg, Sales Ibiza, Sabine Tejpar, Sven Wehner, Gianluca Matteoli   +25 more
doaj   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source