Results 41 to 50 of about 1,115,426 (335)

Laser Doppler flowmetry as a measure of extrinsic colonic innervation in functional bowel disease [PDF]

Gut, 2000
In functional disorders it is unknown whether disturbed function is due to an intrinsic gut abnormality or altered extrinsic innervation.To study whether measurement of mucosal blood flow could be used as a quantitative direct measure of gut extrinsic nerve autonomic activity in patients with idiopathic constipation.Seventy two patients with idiopathic
Anton Emmanuel, Michael A. Kamm
openaire   +2 more sources

Using Corticosteroids to Reshape the Gut Microbiome: Implications for Inflammatory Bowel Diseases

Inflammatory Bowel Diseases, 2015
Background:Commensal gut microbiota play an important role in regulating metabolic and inflammatory conditions. Reshaping intestinal microbiota through pharmacologic means may be a viable treatment option.
Edmond Y. Huang, Takuya Inoue, V. Leone, S. Dalal, Ketrija Touw, Yunwei Wang, M. Musch, B. Theriault, K. Higuchi, S. Donovan, J. Gilbert, E. Chang   +11 more
semanticscholar   +1 more source

Motion-based Camera Localization System in Colonoscopy Videos [PDF]

Medical image analysis. 2021 Oct 1;73:102180, 2020
Optical colonoscopy is an essential diagnostic and prognostic tool for many gastrointestinal diseases, including cancer screening and staging, intestinal bleeding, diarrhea, abdominal symptom evaluation, and inflammatory bowel disease assessment. Automated assessment of colonoscopy is of interest considering the subjectivity present in qualitative ...
arxiv   +1 more source

Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics

The Journal of Physiology, 2012
Abstract  Intestinal barrier dysfunction is a main feature of the inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis. Leak flux diarrhoea and a facilitated uptake of noxious antigens are the two consequences resulting from an impaired epithelial barrier.
Jörg-Dieter Schulzke, Michael Fromm, Nina A. Hering   +2 more
openaire   +4 more sources

Functional CD4+CD25high regulatory T cells are enriched in the colonic mucosa of patients with active ulcerative colitis and increase with disease activity

Inflammatory Bowel Diseases, 2006
Background: Factors determining the extension and degree of inflammation in the colonic mucosa of patients with ulcerative colitis (UC) are largely unknown, but CD4+CD25high regulatory T cells (Tregs) have been implicated to play an important role in ...
N. Holmén, A. Lundgren, S. Lundin, A. Bergin, A. Rudin, H. Sjövall, L. Öhman   +6 more
semanticscholar   +1 more source

Metabolism of Phenolics of Tetrastigma hemsleyanum Roots under In Vitro Digestion and Colonic Fermentation as Well as Their In Vivo Antioxidant Activity in Rats

Foods, 2021
Tetrastigma hemsleyanum Diels et Gilg is a herbaceous perennial species distributed mainly in southern China. The Tetrastigma hemsleyanum root (THR) has been prevalently consumed as a functional tea or dietary supplement.
Yong Sun, Fanghua Guo, Xin Peng, Kejun Cheng, Lu Xiao, Hua Zhang, Hongyan Li, Li Jiang, Zeyuan Deng   +8 more
doaj   +1 more source

Linear Functional Equations and their Solutions in Lorentz Spaces [PDF]

arXiv, 2021
Assume that $\Omega\subset \mathbb{R}^k$ is an open set, $V$ is a separable Banach space over a field $\mathbb K\in\{\mathbb R,\mathbb C\}$ and $f_1,\ldots,f_N \colon\Omega\to \Omega$, $g_1,\ldots, g_N\colon\Omega\to \mathbb{K}$, $h_0\colon \Omega\to V$ are given functions.
arxiv  

Colonic Oxidative and Mitochondrial Function in Parkinson’s Disease and Idiopathic REM Sleep Behavior Disorder [PDF]

Parkinson's Disease, 2017
Objective. To determine potential mitochondrial and oxidative alterations in colon biopsies from idiopathic REM sleep behavior disorder (iRBD) and Parkinson’s disease (PD) subjects. Methods. Colonic biopsies from 7 iRBD subjects, 9 subjects with clinically diagnosed PD, and 9 healthy controls were homogenized in 5% w/v mannitol.
C. Morén, Í. González-Casacuberta, J. Navarro-Otano, D. Juárez-Flores, D. Vilas, G. Garrabou, J. C. Milisenda, C. Pont-Sunyer, M. Catalán-García, M. Guitart-Mampel, E. Tobías, F. Cardellach, F. Valldeoriola, A. Iranzo, E. Tolosa   +14 more
openaire   +5 more sources

Human colonic intraepithelial and lamina proprial lymphocytes: cytotoxicity in vitro and the potential effects of the isolation method on their functional properties.

Gut, 1981
Colonic mucosal lymphoid cells, selectively enriched for intraepithelial (IEL) or lamina proprial lymphocytes (LPL), were isolated by sequential EDTA-collagenase treatment of resected human colons.
M. Chiba, W. Bartnik, S. Remine, W. Thayer, R. G. Shorter   +4 more
semanticscholar   +1 more source

Significance of Ligand-Anchored Polymers for Drug Targeting in the Treatment of Colonic Disorders

Frontiers in Pharmacology, 2020
Treatment of a variety of bowel diseases like Crohn’s disease, ulcerative colitis, colonic cancers, colonic pathologies, and systemic delivery of drugs at the target sites can be done with the help of targeted drug delivery technique.
Pramila Chaubey, Munira Momin, Sujata Sawarkar   +2 more
doaj   +1 more source