Results 21 to 30 of about 90,261 (311)

Microbiota-derived short-chain fatty acids: Implications for cardiovascular and metabolic disease

Frontiers in Cardiovascular Medicine, 2022
Cardiovascular diseases (CVDs) have been on the rise around the globe in the past few decades despite the existing guidelines for prevention and treatment.
Yingdong Lu, Yang Zhang, Xin Zhao, Chang Shang, Mi Xiang, Li Li, Xiangning Cui   +6 more
doaj   +1 more source

DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis

, 2014
Inflammatory bowel diseases (IBD) are emerging globally, indicating that environmental factors may be important in their pathogenesis. Colonic mucosal epigenetic changes, such as DNA methylation, can occur in response to the environment and have been ...
Winter, Harland, Szigeti, Reka, Kaplan, Jess L., Harris, R. Alan, Nagy-Szakal, Dorottya, Kellermayer, Richard, Ferry, George D., Opekun, Antone, Bronsky, Jiri, Mir, Sabina A.V., Frank, Eibe   +10 more
core   +1 more source

Colonic mucus structure and processing [PDF]

, 2018
The mucus layer covering the colonic epithelium creates a crucial first line of defense against the gut residing bacteria. Several lines of evidence suggest that a functional mucus layer is essential for health. For example, it is.
Nyström, Elisabeth
core   +2 more sources

The influence of in vitro gastrointestinal digestion and fecal fermentation on the flowers of Juglans regia: Changes in the active compounds and bioactivities

Frontiers in Nutrition, 2022
The objective of the research was to investigate the digestion and fecal fermentation characteristics of the flowers of Juglans regia (FJR), by using in vitro simulated digestion model (oral, gastric, and intestine) as well as colonic fermentation.
Ximeng Jin, Ximeng Jin, Yuerong Ru, Yuerong Ru, Xuechun Zhang, Xuechun Zhang, Huan Kan, Ping Xiang, Xuemei He, Jian Sun, Xiahong He, Xiahong He, Zhengxing Wang, Zhengxing Wang   +13 more
doaj   +1 more source

Quinoa and Colonic Health: A Review of Bioactive Components and Mechanistic Insights

Current Issues in Molecular Biology
Quinoa (Chenopodium quinoa Willd.) is an ancient Andean crop renowned for its exceptional nutritional profile and diverse bioactive compounds, including polysaccharides, polyphenols, saponins, and essential fatty acids.
Yan Pan, Jimin Zheng, Zhixuan Wang, Shaohua Lin, Hongliang Jia, Hairun Pei, Ronghui Ju   +6 more
doaj   +1 more source

Augmented reduction in colonic inflammatory markers of dextran sulfate sodium-induced colitis with a combination of 5-aminosalicylic acid and AD-lico™ from Glycyrrhiza inflata

Animal Cells and Systems, 2018
The primary aim of this study was to determine whether the oral administration of AD-lico™, a functional extract from Glycyrrhiza inflata in combination with 5-aminosalicylic acid (5-ASA) could ameliorate the inflammatory symptoms in dextran sulfate ...
Jaeyoung Cho, Hyuck-Se Kweon, Sung-Oh Huh, Ali Sadra   +3 more
doaj   +1 more source

Colonic bacterial diversity and dysbiosis in active microscopic colitis as compared to chronic diarrhoea and healthy controls: effect of polyethylene glycol after bowel lavage for colonoscopy

BMC Gastroenterology, 2022
Background Most microbiota studies in microscopic colitis patients are performed after diagnostic colonoscopy without considering the potential effect of colonic lavage.
Lissette Batista, Virginia Robles, Chaysavanh Manichanh, Laura Ruiz, Danila Guagnozzi, Ferran Pinsach, Francisco Guarner, Fernando Fernández-Bañares   +7 more
doaj   +1 more source

The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease. [PDF]

, 2010
Recent evidence suggests a crucial role of the endocannabinoid system, including the cannabinoid 1 receptor (CNR1), in intestinal inflammation. We therefore investigated the influence of the CNR1 1359 G/A (p.Thr453Thr; rs1049353) single nucleotide ...
Brand, Stephan, Burkhard Göke, Göke, Burkhard, Storr, Martin, Göke Burkhard, Ochsenkühn, Thomas, Stephan Brand, Brand Stephan, Thomas Ochsenkühn, Storr Martin, Pfennig, Simone, Dominik Emmerdinger, Peter Lohse, Martin Storr, Emmerdinger Dominik, Diegelmann, Julia, Lohse, Peter, Simone Pfennig, Diegelmann Julia, Emmerdinger, Dominik, Julia Diegelmann, Ochsenkühn Thomas, Lohse Peter, Pfennig Simone   +23 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota [PDF]

, 2011
Objective The gut microbiota, which is considered a causal factor in metabolic diseases as shown best in animals, is under the dual influence of the host genome and nutritional environment. This study investigated whether the gut microbiota per se, aside
Klopp, Christophe, Amar, Jacques, Aurelie Waget, Baylac, Audrey, Waget, Aurélie, Klopp, Pascale, Theodorou, Vassilia, Elodie Luche, Iacovoni, Jason, Francoise Ouarné, Bouloumié, Anne, Jerome Mariette, Pascale Klopp, Klopp, Christophe,, Bergé, Mathieu, Mariette, Jérôme, J., Klopp, Pascal, Remy Burcelin, Serino, Matteo, Burcelin, Rémy, Valet, Philippe, Roques, Christine, Bouchez, Olivier, Matteo Serino, Mathieu Bergé, Jacques Amar, Claire Cenac, Philippe Valet, Monsan, Pierre, Jerome Lluch, Sandra Gres, Mariette, Jérôme,, Christophe Klopp, Christine Roques, Pierre Monsan, Mariette, Jérôme, Jason Iacovoni, Vassilia Théodorou, Cenac, Claire, Lluch, Jérôme, Audrey Baylac, Gres, Sandra, Ouarné, Françoise, Anne Bouloumié, Luche, Elodie, Olivier Bouchez   +45 more
core   +1 more source