Results 11 to 20 of about 90,261 (311)
The Interaction of Large Bowel Microflora with the Colonic Mucus Barrier [PDF]
International Journal of Inflammation, 2010 The colonic mucus barrier is the first line of defence that the underlying mucosa has against the wide range of potentially damaging agents of microbial, endogenous, and dietary origin that occur within the colonic lumen.
Jeffrey P. Pearson, Iain A. Brownlee
doaj +2 more sources
The disturbance of oxidant-antioxidant balance in rat colonic mucosa after antibiotic therapy
Біологічні студії, 2015 Antibiotic treatment increases susceptibility to development of inflammatory bowel diseases (IBD) both in children and adults. Oxidative stress plays a prominent role in IBD pathogenesis.
Y. Holota +3 more
doaj +2 more sources
Human gut microbiota-reactive DP8α regulatory T cells, signature and related emerging functions
Frontiers in Immunology, 2022 In mice, microbiota-induced Tregs both maintain intestinal homeostasis and provide resistance to immuno-pathologies in the adult. Identifying their human functional counterpart therefore represents an important goal.
Francine Jotereau +6 more
doaj +1 more source
Gut Microbes, 2023 Colibactin, a bacterial genotoxin produced by E. coli strains harboring the pks genomic island, induces cytopathic effects, such as DNA breaks, cell cycle arrest, and apoptosis.
Christine Harnack +5 more
doaj +1 more source
Clinical Parasitology and Parasitome Maps as Old and New Tools to Improve Clinical Microbiomics
Pathogens, 2021 A growing body of evidence shows that dysbiotic gut microbiota may correlate with a wide range of disorders; hence, the clinical use of microbiota maps and fecal microbiota transplantation (FMT) can be exploited in the clinic of some infectious diseases.
Stefania Pane +5 more
doaj +1 more source
Cells, 2022 Thanks to the latest developments in mass spectrometry, software and standards, metaproteomics is emerging as the vital complement of metagenomics, to make headway in understanding the actual functioning of living and active microbial communities. Modern
Céline Henry +5 more
doaj +1 more source
مجله دانشکده پزشکی اصفهان, 2018 Background: Chronic functional constipation is one of functional gastrointestinal disorders. Constipation has negative impact on quality of life (QOL). Pharmacological and non-pharmacological treatments are considered for constipation.
Mansour Bahardoost +6 more
doaj +1 more source
The Proinflammatory Role of Guanylate-Binding Protein 5 in Inflammatory Bowel Diseases
Frontiers in Microbiology, 2022 NLRP3 inflammasome is implicated in the pathogenesis of inflammatory bowel diseases (IBD). Since guanylate-binding protein 5 (GBP5) induces the NLRP3 inflammasome activity, we aim to investigate the potential role of GBP5 in IBD pathogenesis.
Yichen Li +9 more
doaj +1 more source
Potassium channels in prostate and colonic cancer
, 2007 Large conductance Ca2+-activated K+ channels in human prostate cancer The KCNMA1 gene encoding the alpha-subunit of BK channels is amplified and BK channel expression is enhanced in late-stage, metastatic and hormone-refractory human prostate cancer ...
Ousingsawat, Jiraporn
core +1 more source
Scientific Reports, 2022 Humans have long-used mushrooms as food and medicine, but digestion and colonic fermentation of most mushrooms, including Lentinus squarrosulus is markedly unknown. Here, nutritional profile, digestion and colonic fermentation of L.
Francis Ayimbila +3 more
doaj +1 more source