Results 61 to 70 of about 1,115,426 (335)

Autologous cell transplantation for treatment of colorectal aganglionosis in mice

Nature Communications
Neurointestinal diseases cause significant morbidity and effective treatments are lacking. This study aimes to test the feasibility of transplanting autologous enteric neural stem cells (ENSCs) to rescue the enteric nervous system (ENS) in a model of ...
Weikang Pan, Ahmed A. Rahman, Takahiro Ohkura, Rhian Stavely, Kensuke Ohishi, Christopher Y. Han, Abigail Leavitt, Aki Kashiwagi, Alan J. Burns, Allan M. Goldstein, Ryo Hotta   +10 more
doaj   +1 more source

Machine Learning-based Lung and Colon Cancer Detection using Deep Feature Extraction and Ensemble Learning [PDF]

arXiv, 2022
Cancer is a fatal disease caused by a combination of genetic diseases and a variety of biochemical abnormalities. Lung and colon cancer have emerged as two of the leading causes of death and disability in humans. The histopathological detection of such malignancies is usually the most important component in determining the best course of action.
arxiv  

Hirschsprung's disease: functional and psychological follow up comparing total colonic and rectosigmoid aganglionosis [PDF]

Archives of Disease in Childhood, 2002
To compare the long term functional and psychosocial outcomes following surgical treatment for total colonic aganglionosis (TCA) with those in an age and gender matched group of patients with rectosigmoid aganglionosis (RSA).Fifteen patients with TCA matched for age and gender with 15 patients with RSA were studied 7-17 years after the definitive ...
Agostino Pierro, H Tsuji, Lewis Spitz, L Ludman   +3 more
openaire   +2 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

A Study on the Relationship between Dietary Patterns and Prevalence of Irritable Bowel Syndrome

پزشکی بالینی ابن سینا, 2015
Introduction & Objective: Although several dietary factors have been reported to alleviate or ag-gravate the symptoms of irritable bowel syndrome (IBS), no information is available linking dietary patterns to irritable bowel syndrome.
Omid Sadeghi, Seyyed Saeed Khayyatzadeh, Ahmad Esmaillzadeh, Ammar Hasanzadeh Keshteli, Peyman Adibi   +4 more
doaj  

The Exopolysaccharide Produced by Lactobacillus paracasei IJH-SONE68 Prevents and Ameliorates Inflammatory Responses in DSS–Induced Ulcerative Colitis

Microorganisms, 2021
Inflammatory bowel disease (IBD) is an autoimmune disease characterized by chronic inflammation of the gastrointestinal tract. IBD includes Crohn’s disease (CD) and ulcerative colitis (UC).
Masafumi Noda, Narandalai Danshiitsoodol, Keishi Kanno, Tomoyuki Uchida, Masanori Sugiyama   +4 more
doaj   +1 more source

Detecting ulcerative colitis from colon samples using efficient feature selection and machine learning [PDF]

arXiv, 2020
Ulcerative colitis (UC) is one of the most common forms of inflammatory bowel disease (IBD) characterized by inflammation of the mucosal layer of the colon. Diagnosis of UC is based on clinical symptoms, and then confirmed based on endoscopic, histologic and laboratory findings.
arxiv  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

BHCMDA: A New Biased Heat Conduction Based Method for Potential MiRNA-Disease Association Prediction

Frontiers in Genetics, 2020
Recent studies have indicated that microRNAs (miRNAs) are closely related to sundry human sophisticated diseases. According to the surmise that functionally similar miRNAs are more likely associated with phenotypically similar diseases, researchers have ...
Xianyou Zhu, Xuzai Wang, Haochen Zhao, Tingrui Pei, Linai Kuang, Linai Kuang, Lei Wang, Lei Wang   +7 more
doaj   +1 more source