Results 231 to 240 of about 177,298 (308)

DNA Barcoding‐Enabled Tracking of Lipid Nanoparticles: Drug‐Loading‐Dependent Biodistribution and Tumor Microenvironment Targeting

Advanced Healthcare Materials, EarlyView.
In this study, lipid nanoparticles are tracked in vivo using DNA barcodes to determine how varying drug loadings affect their delivery behaviors in mice. A cost‐effective strategy is developed for simultaneously monitoring the biodistribution of a library of lipid nanoparticles (LNPs).
Letao Xu, Rui Chen, Xing Wang, Dawei Liu, Yun liu, Chun‐Xia Zhao   +5 more
wiley   +1 more source

Cathelicidin regulates goblet cell mucus secretion and mucus-associated proteins in <i>Citrobacter rodentium</i>-induced colitis. [PDF]

Gut Microbes
Mirzadzare N, Blyth GAD, Hannawayya R, Cirone KM, Kilari G, Lahiri P, Tan YL, Herik AI, Fu Y, Gorman H, Petri B, Chadee K, Cobo ER.   +12 more
europepmc   +1 more source

Practical Guide to the Design of Granular Hydrogels for Customizing Complex Cellular Microenvironments

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley   +1 more source

The host genes influencing <i>Clostridioides difficile</i> infection and the potential role of intestinal Lactobacillus acidophilus: a Mendelian randomization and animal model study. [PDF]

Front Cell Infect Microbiol
Sun Y, Zhou W, Ma S, Lu Q, Yuan Y, Zheng Y, Yang Y, Zhou K, Chen Q, Sun G, Shang Z, Qian J, Jiang X, Chen M.   +13 more
europepmc   +1 more source

Phase III study of granulocyte-macrophage colony-stimulating factor in advanced HIV disease: effect on infections, CD4 cell counts and HIV suppression

, 2000
Jonathan B. Angel, Kevin P. High, Frank S. Rhame, David Brand, James B. Whitmore, Jan M. Agosti, M. Jean Gilbert, Stanley C. Deresinski   +7 more
openalex   +1 more source

Roll‐To‐Roll Production of Smart Dressings for Wound Monitoring

Advanced Healthcare Materials, EarlyView.
This study presents a roll‐to‐roll manufactured smart wound dressing capable of visually monitoring key wound biomarkers, including pH, humidity, and temperature. By integrating colorimetric sensors into flexible dressing substrates, the device offers real‐time, equipment‐free insights for infection detection and wound management, representing a ...
Ziheng Wang, Yujin Ahn, Semin Kwon, Tianhao Yu, Yumin Dai, Julia Walsh, Joo Hun Lee, Sang Mok Park, Seul Ah Lee, Murtuza Peerbhai, Chandan K. Sen, Hyowon Lee, Young L. Kim, Hyunjoon Kong, Chi Hwan Lee   +14 more
wiley   +1 more source

Acute toxic megacolon in visceral myopathy: A rare and challenging case report with literature review. [PDF]

Medicine (Baltimore)
Al-Tartir A, Sbitan L, Imhaisen M, Al-Zubi A, Farhat H.   +4 more
europepmc   +1 more source

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

An adeno-associated virus gene therapy strategy for anti-obesity treatment by nanocarrier-based delivery systems. [PDF]

J Nanobiotechnology
Li L, Wang W, Li R, Guo J, Hu X, Pan Y, Zhang T, Chi S, Gu Z, Zhu G, Liu Q, Tan S.   +11 more
europepmc   +1 more source

A Case Report of Diverticular Disease of the Sigmoid Colon with Colonic Muco-submucosal Elongated Polyp.

, 2000
Yoshifumi Nakayama, Koji Kadowaki, Aiichiro Higure, Naoki Nagata, H. Itoh   +4 more
openalex   +2 more sources