Results 281 to 290 of about 9,470,889 (359)

Characterization of Inflammatory Bowel Disease Heterogeneity Using Serum Proteomics: A Multicenter Study. [PDF]

J Crohns Colitis
Salomon B, Sudhakar P, Bergemalm D, Andersson E, Grännö O, Carlson M, Hedin CRH, Söderholm JD, Öhman L, BIO IBD Consortium, the COLLIBRI Consortium , Lindqvist CM, Kruse R, Repsilber D, Verstockt B, Vermeire S, Halfvarson J, Halfvarson J.   +17 more
europepmc   +1 more source

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

Advanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang, Yousheng Wu, Xuanlin Su, Kaiwei Cai, Man Ke, Niu He, Huili Zhu, Zefeng Tan, Jielin Zhu, Wensheng He, Min Peng, Shiqing Zhang, Hongcheng Mai, Anding Xu, Dan Lu   +14 more
wiley   +1 more source

Involvement of the NLRP3/IL-1β pathway in activation and effector functions of γδT17 cells in patients with ulcerative colitis. [PDF]

World J Gastroenterol
Ma J, Wang FY, Tang XD.
europepmc   +1 more source

The CRL7FBXW8 Complex Controls the Mammary Stem Cell Compartment through Regulation of NUMB Levels

Advanced Science, EarlyView.
In breast cancer (BC), NUMB loss of function (LOF) is common and mainly driven by protein hyper‐degradation. The CRL7FBXW8 complex is the E3 ligase responsible for NUMB degradation. Inhibition of CRL7FBXW8 in NUMB‐LOF BC cells restores NUMB levels, and decreases the number of cancer stem cells and tumorigenic ability in vivo. Targeting CRL7FBXW8 offers
Simone Sabbioni, Maria Grazia Filippone, Letizia Amadori, Stefano Confalonieri, Roberta Bonfanti, Stefano Capoano, Ivan Nicola Colaluca, Stefano Freddi, Giovanni Bertalot, Giovanni Fagà, Elisa Zagarrí, Mario Varasi, Rosalind Helen Gunby, Ciro Mercurio, Salvatore Pece, Pier Paolo Di Fiore, Daniela Tosoni   +16 more
wiley   +1 more source

Suramin Exerts an Ameliorative Effect on Acetic Acid-Induced Acute Colitis in Rats by Demonstrating Potent Antioxidant and Anti-Inflammatory Properties. [PDF]

Medicina (Kaunas)
Ercan G, Aygün H, Akbaş A, Çınaroğlu OS, Erbas O.   +4 more
europepmc   +1 more source

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

Aging-related impairment of neurogenic chloride secretion in human colon mucosa. [PDF]

Front Physiol
Wang R, He J, Yang P, Bai T, Song J, Hou X, Zhang L.   +6 more
europepmc   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

Escherichia coli Nissle Improves Short-Chain Fatty Acid Absorption and Barrier Function in a Mouse Model for Chronic Inflammatory Diarrhea. [PDF]

Inflamm Bowel Dis
Ye Z, Tan Q, Woltemate S, Tan X, Römermann D, Grassl GA, Vital M, Seidler U, Kini A.   +8 more
europepmc   +1 more source