Results 61 to 70 of about 2,355,621 (296)

Minilaparotomias para tratamento de doenças do cólon

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Estudar as possibilidades técnicas e resultados obtidos com pequenas incisões para tratar doenças do cólon. MÉTODO: Vinte e seis pacientes, 12 do sexo masculino e 14 do feminino foram submetidos a laparotomias com incisões menores que 10cm.
Peretz Capelhuchnik, Paulo de Azeredo Passos Candelária, Chia Bin Fang, Wilmar Artur Klug, Jorge Alberto Ortiz   +4 more
doaj   +1 more source

CD300b regulates intestinal inflammation and promotes repair in colitis

Frontiers in Immunology, 2023
Chronic inflammation is a hallmark charataristic of various inflammatory diseases including inflammatory bowel disease. Subsequently, current therapeutic approaches target immune-mediated pathways as means for therapeutic intervention and promotion of ...
Shmuel Avlas, Hala Kassis, Michal Itan, Hadar Reichman, Avishay Dolitzky, Inbal Hazut, Sharon Grisaru-Tal, Yaara Gordon, Ilan Tsarfaty, Danielle Karo-Atar, Perri Rozenberg, Almog Bitton, Ariel Munitz   +12 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A Review on Pharmacological and Therapeutical Insight of Satranidazole for Colon Targeting in the treatment of Colonic Diseases [PDF]

, 2022
Drugs targeting the colonic environment to treat various colonic diseases are the major challenges recently. Various drugs are available in the markets to targeting to the colonic region to treat diseases but due to premature drug releases, target ...
Ghosh, Soumyadip, Chowdhury, Ananta, Majumder, Subhabrota, Ganguly, Debgopal   +3 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Pathways involved in gut mucosal barrier dysfunction induced in adult rats by maternal deprivation: corticotrophin-releasing factor and nerve growth factor interplay [PDF]

, 2007
Neonatal maternal deprivation (NMD) increases gut paracellular permeability (GPP) through mast cells and nerve growth factor (NGF), and modifies corticotrophin-releasing factor (CRF) and corticosterone levels.
Lionel Bueno, Ferrier, Laurent, Fioramonti, Jean, Mathilde Leveque, Cartier, Christel, Frederick Barreau, Raphael Moriez, Valerie Laroute, Laurent Ferrier, Andras Rosztoczy, Christel Cartier, Leveque, Mathilde, Rosztoczy, Andras, Jean Fioramonti, Barreau, Frederick, Laroute, Valerie, Moriez, Raphael, Bueno, Lionel   +17 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Comparison of the Effect of the Routine Bowel Preparation and Use of Oral Sodium Phosphate on Acceptance and Bowel Cleansing in Patients Undergoing Colonoscopy: A Randomize Clinical Trial

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2010
Background and Objectives: Treatment team perform a variety of practices in the fields of treatment and caring. The main domain of nursing practice is to prepare patients for diagnostic tests.
A Ghanbari, M Ebrahim Musavi, M Yusefi Mash’hur, T Khaleghdoost, Z Atrkar Roshan   +4 more
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source