Results 51 to 60 of about 180,158 (258)

Comparison of the Effect of the Routine Bowel Preparation and Use of Oral Sodium Phosphate on Acceptance and Bowel Cleansing in Patients Undergoing Colonoscopy: A Randomize Clinical Trial

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2010
Background and Objectives: Treatment team perform a variety of practices in the fields of treatment and caring. The main domain of nursing practice is to prepare patients for diagnostic tests.
A Ghanbari, M Ebrahim Musavi, M Yusefi Mash’hur, T Khaleghdoost, Z Atrkar Roshan   +4 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

COLONIC IRRIGATION AND AGING: HYPOTHETICAL INSIGHTS INTO INFLAMMATION REDUCTION

Anti-Aging Eastern Europe
Colonic irrigation (colon hydrotherapy) is a procedure where water is applied to clean the colon of the contents it holds. Colonic irrigation has a theoretical rationale for improving systemic inflammation and gastrointestinal health.
Ilke Coskun Benlidayi
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A Study on the Relationship between Dietary Patterns and Prevalence of Irritable Bowel Syndrome

پزشکی بالینی ابن سینا, 2015
Introduction & Objective: Although several dietary factors have been reported to alleviate or ag-gravate the symptoms of irritable bowel syndrome (IBS), no information is available linking dietary patterns to irritable bowel syndrome.
Omid Sadeghi, Seyyed Saeed Khayyatzadeh, Ahmad Esmaillzadeh, Ammar Hasanzadeh Keshteli, Peyman Adibi   +4 more
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Frequency of Thyroid Nodules among Patients with Colonic Polyps

Gastroenterology Research and Practice, 2012
Aim. Colonic polyps and thyroid nodules are common diseases and their frequency increases with age. In the literature, there is no study investigating the coexistence of colonic polyps and thyroid nodules.
Cevdet Duran, Huseyin Savas Gokturk, Mustafa Kulaksizoglu, Suleyman Bakdik, Gulhan Kanat Unler, Mustafa Erbayrak, Guven Ozkaya, Baris Onder Pamuk, Mustafa Sait Gonen   +8 more
doaj   +1 more source

Minimally Invasive Methods of Temporary Decompression of the Colon with Obturation Colonic Obstruction: a Literature Review

Неотложная медицинская помощь, 2019
Colorectal cancer is one of the most common oncological diseases. In 40–60% of cases, patients with colorectal cancer enter general surgical hospitals with complications.
D. I. Petrov, P. A. Yartsev, D. A. Blagovestnov, V. D. Levitsky, B. T. Tsuleiskiri, I. I. Kirsanov, M. M. Rogal   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source