Results 31 to 40 of about 2,355,621 (296)
Guidelines for inflammation models in mice for food components
eFood, 2022 Inflammation is one of the major health threats to humans, and it is associated with various chronic diseases, including metabolic syndrome, type 2 diabetes, cardiovascular diseases, and several types of cancer.
Yanhui Han +3 more
doaj +1 more source
Rapid establishment of human colonic organoid knockout lines
STAR Protocols, 2022 Summary: Human colonic organoids derived from biopsy or autopsy tissues are a vital tool to study mucosal homeostasis, model colonic diseases, and develop therapeutics. Rapid and reliable generation of knockout organoid lines from multiple donors enables
Wei Gu +4 more
doaj +1 more source
Clinics in Colon and Rectal Surgery, 2007 Crohn's disease is an inflammatory disease of the gastrointestinal (GI) tract of uncertain etiology. It can affect any portion of the GI tract, involving the colon in approximately 60% of cases. Diagnosis can be unclear, but suspicion can be raised based upon clinical, endoscopic, and pathologic findings.
Steven, Mills, Michael J, Stamos
openaire +2 more sources
Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset. [PDF]
, 2010 Recent studies demonstrated an association of STAT4 variants with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), indicating that multiple autoimmune diseases share common susceptibility genes. We therefore investigated the influence of
Seiderer, J. +69 more
core +2 more sources
Endoscopy International OpenBackgrounds and study aim Placement of a self-expandable metallic stent (SEMS) has become a common practice for obstructive colorectal cancer. However, the safety and efficacy of systemic chemotherapy after SEMS placement remain unclear.
Akihisa Matsuda +29 more
doaj +1 more source
Volvulus U-Shaped transverse colonic duplication: Report of a case and literature review
Journal of Pediatric Surgery Case Reports, 2017 Tubular duplication of the colon is very rare especially in adulthood, because it is frequently symptomatic earlier in newborn life, so only few cases are reported in literature. Several theories are proposed to explain the onset and the evolution of gut
Ruankha Bilommi
doaj +1 more source
Management of left-sided malignant colonic obstruction : an audit of a stent based protocol [PDF]
, 2011 Includes abstract.Includes bibliographical references.Colonic self-expanding metallic stents (SEMS) are proven to be safe and effective in the management of selected cases of malignant colonic obstruction.
Warden, C
core +1 more source
Establishment of porcine and monkey colonic organoids for drug toxicity study
Cell Regeneration, 2021 Pig and monkey are widely used models for exploration of human diseases and evaluation of drug efficiency and toxicity, but high cost limits their uses.
Haonan Li +7 more
doaj +1 more source
Acta Medica Iranica, 2023 Changes in the expression of nucleotide-binding oligomerization domain containing 2 (NOD2) play an important role in the pathogenesis of several autoimmune diseases, such as inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ...
Golshid Sanati +6 more
doaj +1 more source
MYOD-1 in normal colonic mucosa : role as a putative biomarker? [PDF]
, 2012 Background DNA methylation of promoter-associated CpG islands of certain genes may play a role in the development of colorectal cancer. The MYOD-1 gene which is a muscle differentiation gene has been showed to be significantly methylated in colorectal ...
Mathers, John +18 more
core +1 more source