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Progress in the treatment of colonic diverticular diseases [PDF]
Waike lilun yu shijianThe incidence of colonic diverticular disease is increasing significantly and is showing a trend of youthfulness. The treatment of colonic diverticulum disease mainly involves drugs, including antibiotics, rifaximin, and mesalazine.
KONG Lei, YANG Huali
doaj +3 more sources
Post-Translational Modifications of Transcription Factors Harnessing the Etiology and Pathophysiology in Colonic Diseases. [PDF]
Int J Mol Sci, 2020 [[abstract]]Defects in mucosal immune balance can lead to colonic diseases such as inflammatory bowel diseases and colorectal cancer. With the advancement of understanding for the immunological and molecular basis of colonic disease, therapies targeting ...
Hsu CY +5 more
europepmc +3 more sources
Biofilms and Benign Colonic Diseases. [PDF]
Int J Mol Sci, 2022 The colon has a very large surface area that is covered by a dense mucus layer. The biomass in the colon includes 500–1000 bacterial species at concentrations of ~1012 colony-forming units per gram of feces.
Songtanin B +3 more
europepmc +2 more sources
K-ras and p53 mutations in colonic lavage fluid of patients with colorectal neoplasias [PDF]
, 2001 Background: The adenoma-carcinoma sequence has its molecular basis in several gene mutations of which K-ras and p53 are of paramount importance. The aims of this study were to evaluate whether these genetic alterations can be detected in colonic lavage ...
Folwaczny, Christian +3 more
core +2 more sources
Fibrinolysis in colonic disease [PDF]
Gut, 1970 Fibrinolytic activity of colic venous and arterial blood has been studied at laparotomy in 18 patients with ulcerative colitis or Crohn's colitis and compared with that of 17 patients with colonic carcinoma or diverticulosis. Using the dilute blood clot lysis time technique, no difference was detected between the fibrinolytic activity in colic venous ...
C H, Swan, J A, Williams, W T, Cooke
openaire +2 more sources
DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis [PDF]
, 2014 Inflammatory bowel diseases (IBD) are emerging globally, indicating that environmental factors may be important in their pathogenesis. Colonic mucosal epigenetic changes, such as DNA methylation, can occur in response to the environment and have been ...
Winter, Harland +10 more
core +1 more source
Dietary calcium decreases but short-chain fructo-oligosaccharides increase colonic permeability in rats [PDF]
, 2010 An increased intestinal permeability is associated with several diseases. Nutrition can influence gut permeability. Previously, we showed that dietary Ca decreases whereas dietary short-chain fructo-oligosaccharides (scFOS) increase intestinal ...
Schepens, M.A.A. +28 more
core +1 more source
Clinics in Colon and Rectal Surgery, 2013 Colonic Crohn disease is a complicated disease entity that requires a multidisciplinary effort on the part of the surgeon, gastroenterologist, and pathologist. Crohn disease affects ∼500,000 people in North America with nearly 300,000 people suffering from colonic manifestations.
Traci L, Hedrick, Charles M, Friel
openaire +2 more sources
Pharmacogenetics and diseases of the colon [PDF]
Current Opinion in Gastroenterology, 2007 The deciphering of the human genome sequence has enabled the identification of genetic polymorphisms that are responsible for inter-individual variation in the response to drug therapy. This field is referred to as pharmacogenetics. We review the impact of pharmacogenetics on therapy in diseases of the colon using three common variant enzyme systems as
Irfan M, Hisamuddin +2 more
openaire +2 more sources