Pharmacogenetics and diseases of the colon [PDF]
Current Opinion in Gastroenterology, 2007 The deciphering of the human genome sequence has enabled the identification of genetic polymorphisms that are responsible for inter-individual variation in the response to drug therapy. This field is referred to as pharmacogenetics. We review the impact of pharmacogenetics on therapy in diseases of the colon using three common variant enzyme systems as
Irfan M, Hisamuddin +2 more
openaire +2 more sources
The Irritated Gastro-Intestinal Syndome: The Role of Dietary Rehabilitation
South African Family Practice, 1991 No abstract available.
G. Borok, I. Segal
doaj +1 more source
Chronic partial colonic obstruction from a congenital web
Journal of Pediatric Surgery Case Reports, 2020 Congenital colonic stenosis is a rare anomaly that mostly presents in the neonatal period with colonic obstruction. The similarity of presentation with Hirschsprung diseases prompts discussion on suspicion, detection and management.
Timothy Jumbi, Peter Mwika
doaj +1 more source
MRISCs protect colonic stem cells from inflammatory damage
Cell Regeneration, 2021 Increasing evidence suggest functional roles of subepithelial mesenchymal niche cells in maintaining intestinal stem cells and in modulating the pathogenesis of various intestinal diseases in mammals.
Guoli Zhu, Rongwen Xi
doaj +1 more source
Acute Colonic Pseudo-obstruction Induced by Neuroleptic Malignant Syndrome
The Korean Journal of Gastroenterology, 2021 A colonic pseudo-obstruction is a disorder that causes abdominal distension and abdominal pain similar to a mechanical obstruction, but there are no structural lesions that can obstruct the gastrointestinal tract.
Sung Ju Ryu +2 more
doaj +1 more source
Idiopathic Nonobstructive Colo-colonic Intussusception: A Rare Clinical Presentation
Turkish Journal of Colorectal Disease, 2019 Adult intussusception is a rare clinical condition. There is generally an etiological factor, mainly malignancy. However, the number of idiopathic cases is very low.
Fatma Ayça Gültekin +2 more
doaj +1 more source
Dolichocolon: A Narrative Review of an under-Recognized Disorder [PDF]
Iranian Journal of Colorectal ResearchDolichocolon is an anatomical variant that is often under-recognized but has significant clinical implications.It is characterized by an abnormally elongated and redundant colon, distinguishing it from megacolon,which involves an increase in the colon’s ...
Sajad Ahmad Salati
doaj +1 more source
The amount of keratins matters for stress protection of the colonic epithelium. [PDF]
PLoS ONE, 2015 Keratins (K) are important for epithelial stress protection as evidenced by keratin mutations predisposing to human liver diseases and possibly inflammatory bowel diseases.
M Nadeem Asghar +7 more
doaj +1 more source
Evaluation of Plasma M2-Pyruvate Kinase as A Novel Biomarker in The Differentiation Between Functional and Organic Colonic Disorders [PDF]
Ain Shams Medical JournalBackground: It is challenging to distinguish between functional and organic colonic disorders because they can exhibit similar symptoms, with the exception of organic disorders that exhibit red flag symptoms including anemia, weight loss or bleeding per ...
Ahmed Ahmed +4 more
doaj +1 more source
Challenges and Future of Wireless Capsule Endoscopy [PDF]
Clinical Endoscopy, 2016 In 2015, capsule endoscopy was introduced as the main investigation method for small bowel mucosal diseases, and its role in colonic diseases has been gradually revealed.
Jean-Christophe Saurin +3 more
doaj +1 more source