Results 21 to 30 of about 180,490 (257)
Crohn's disease is an inflammatory disease of the gastrointestinal (GI) tract of uncertain etiology. It can affect any portion of the GI tract, involving the colon in approximately 60% of cases. Diagnosis can be unclear, but suspicion can be raised based upon clinical, endoscopic, and pathologic findings.
Steven, Mills, Michael J, Stamos
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Lente van Kessel, Doreth Teunissen, Toine Lagro-Janssen Department of Primary and Community Care / Gender and Women’s Health, Radboud University Medical Centre, Nijmegen, the NetherlandsCorrespondence: Lente van Kessel Multatuliplaats 18A, Nijmegen,
van Kessel L +2 more
doaj
Colonic Crohn disease is a complicated disease entity that requires a multidisciplinary effort on the part of the surgeon, gastroenterologist, and pathologist. Crohn disease affects ∼500,000 people in North America with nearly 300,000 people suffering from colonic manifestations.
Traci L, Hedrick, Charles M, Friel
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Backgrounds and study aim Placement of a self-expandable metallic stent (SEMS) has become a common practice for obstructive colorectal cancer. However, the safety and efficacy of systemic chemotherapy after SEMS placement remain unclear.
Akihisa Matsuda +29 more
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Volvulus U-Shaped transverse colonic duplication: Report of a case and literature review
Tubular duplication of the colon is very rare especially in adulthood, because it is frequently symptomatic earlier in newborn life, so only few cases are reported in literature. Several theories are proposed to explain the onset and the evolution of gut
Ruankha Bilommi
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Guidelines for inflammation models in mice for food components
Inflammation is one of the major health threats to humans, and it is associated with various chronic diseases, including metabolic syndrome, type 2 diabetes, cardiovascular diseases, and several types of cancer.
Yanhui Han +3 more
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Rapid establishment of human colonic organoid knockout lines
Summary: Human colonic organoids derived from biopsy or autopsy tissues are a vital tool to study mucosal homeostasis, model colonic diseases, and develop therapeutics. Rapid and reliable generation of knockout organoid lines from multiple donors enables
Wei Gu +4 more
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Maternal antibiotic-induced early changes in microbial colonization selectively modulate colonic permeability and inducible heat shock proteins, and digesta concentrations of alkaline phosphatase and TLR-stimulants in swine offspring. [PDF]
Elevated intake of high energy diets is a risk factor for the development of metabolic diseases and obesity. High fat diets cause alterations in colonic microbiota composition and increase gut permeability to bacterial lipopolysaccharide, and subsequent ...
Marie-Edith Arnal +4 more
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Changes in the expression of nucleotide-binding oligomerization domain containing 2 (NOD2) play an important role in the pathogenesis of several autoimmune diseases, such as inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ...
Golshid Sanati +6 more
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Establishment of porcine and monkey colonic organoids for drug toxicity study
Pig and monkey are widely used models for exploration of human diseases and evaluation of drug efficiency and toxicity, but high cost limits their uses.
Haonan Li +7 more
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