Results 21 to 30 of about 180,158 (258)
Clinics in Colon and Rectal Surgery, 2007 Crohn's disease is an inflammatory disease of the gastrointestinal (GI) tract of uncertain etiology. It can affect any portion of the GI tract, involving the colon in approximately 60% of cases. Diagnosis can be unclear, but suspicion can be raised based upon clinical, endoscopic, and pathologic findings.
Steven, Mills, Michael J, Stamos
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Volvulus U-Shaped transverse colonic duplication: Report of a case and literature review
Journal of Pediatric Surgery Case Reports, 2017 Tubular duplication of the colon is very rare especially in adulthood, because it is frequently symptomatic earlier in newborn life, so only few cases are reported in literature. Several theories are proposed to explain the onset and the evolution of gut
Ruankha Bilommi
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Guidelines for inflammation models in mice for food components
eFood, 2022 Inflammation is one of the major health threats to humans, and it is associated with various chronic diseases, including metabolic syndrome, type 2 diabetes, cardiovascular diseases, and several types of cancer.
Yanhui Han +3 more
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Rapid establishment of human colonic organoid knockout lines
STAR Protocols, 2022 Summary: Human colonic organoids derived from biopsy or autopsy tissues are a vital tool to study mucosal homeostasis, model colonic diseases, and develop therapeutics. Rapid and reliable generation of knockout organoid lines from multiple donors enables
Wei Gu +4 more
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Clinics in Colon and Rectal Surgery, 2013 Colonic Crohn disease is a complicated disease entity that requires a multidisciplinary effort on the part of the surgeon, gastroenterologist, and pathologist. Crohn disease affects ∼500,000 people in North America with nearly 300,000 people suffering from colonic manifestations.
Traci L, Hedrick, Charles M, Friel
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Establishment of porcine and monkey colonic organoids for drug toxicity study
Cell Regeneration, 2021 Pig and monkey are widely used models for exploration of human diseases and evaluation of drug efficiency and toxicity, but high cost limits their uses.
Haonan Li +7 more
doaj +1 more source
Acta Medica Iranica, 2023 Changes in the expression of nucleotide-binding oligomerization domain containing 2 (NOD2) play an important role in the pathogenesis of several autoimmune diseases, such as inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ...
Golshid Sanati +6 more
doaj +1 more source
Maternal antibiotic-induced early changes in microbial colonization selectively modulate colonic permeability and inducible heat shock proteins, and digesta concentrations of alkaline phosphatase and TLR-stimulants in swine offspring. [PDF]
PLoS ONE, 2015 Elevated intake of high energy diets is a risk factor for the development of metabolic diseases and obesity. High fat diets cause alterations in colonic microbiota composition and increase gut permeability to bacterial lipopolysaccharide, and subsequent ...
Marie-Edith Arnal +4 more
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Endoscopic Management of Benign Colonic Obstruction and Pseudo-Obstruction [PDF]
Clinical Endoscopy, 2020 There are a variety of causes of intestinal obstruction, with the most common cause being malignant diseases; however, volvulus, inflammatory bowel disease or diverticulitis, radiation injury, ischemia, and pseudo-obstruction can also cause colonic ...
Su Jin Jeong, Jongha Park
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source