K-ras and p53 mutations in colonic lavage fluid of patients with colorectal neoplasias [PDF]
Background: The adenoma-carcinoma sequence has its molecular basis in several gene mutations of which K-ras and p53 are of paramount importance. The aims of this study were to evaluate whether these genetic alterations can be detected in colonic lavage ...
Folwaczny, Christian +3 more
core +1 more source
DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis [PDF]
Inflammatory bowel diseases (IBD) are emerging globally, indicating that environmental factors may be important in their pathogenesis. Colonic mucosal epigenetic changes, such as DNA methylation, can occur in response to the environment and have been ...
Bronsky, Jiri +10 more
core +2 more sources
Beneficial effect of voluntary exercise on experimental colitis in mice fed a high-fat diet : the role of irisin, adiponectin and proinflammatory biomarkers [PDF]
Inflammatory bowel diseases (IBDs) are a heterogeneous group of disorders exhibited by two major phenotypic forms: Crohn‘s disease and ulcerative colitis.
Bilski, Jan +10 more
core +1 more source
Dolichocolon: A Narrative Review of an under-Recognized Disorder [PDF]
Dolichocolon is an anatomical variant that is often under-recognized but has significant clinical implications.It is characterized by an abnormally elongated and redundant colon, distinguishing it from megacolon,which involves an increase in the colon’s ...
Sajad Ahmad Salati
doaj +1 more source
Alteration of colonic excitatory tachykininergic motility and enteric inflammation following dopaminergic nigrostriatal neurodegeneration [PDF]
Background: Parkinson's disease (PD) is frequently associated with gastrointestinal (GI) symptoms, including constipation and defecatory dysfunctions. The mechanisms underlying such disorders are still largely unknown, although the occurrence of a bowel ...
Antonioli, Luca +13 more
core +3 more sources
Chronic partial colonic obstruction from a congenital web
Congenital colonic stenosis is a rare anomaly that mostly presents in the neonatal period with colonic obstruction. The similarity of presentation with Hirschsprung diseases prompts discussion on suspicion, detection and management.
Timothy Jumbi, Peter Mwika
doaj +1 more source
Acute Colonic Pseudo-obstruction Induced by Neuroleptic Malignant Syndrome
A colonic pseudo-obstruction is a disorder that causes abdominal distension and abdominal pain similar to a mechanical obstruction, but there are no structural lesions that can obstruct the gastrointestinal tract.
Sung Ju Ryu +2 more
doaj +1 more source
Lente van Kessel, Doreth Teunissen, Toine Lagro-Janssen Department of Primary and Community Care / Gender and Women’s Health, Radboud University Medical Centre, Nijmegen, the NetherlandsCorrespondence: Lente van Kessel Multatuliplaats 18A, Nijmegen,
van Kessel L +2 more
doaj
MRISCs protect colonic stem cells from inflammatory damage
Increasing evidence suggest functional roles of subepithelial mesenchymal niche cells in maintaining intestinal stem cells and in modulating the pathogenesis of various intestinal diseases in mammals.
Guoli Zhu, Rongwen Xi
doaj +1 more source

