Results 111 to 120 of about 59,560 (374)
Molecular Oncology, EarlyView.This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto +3 more
wiley +1 more source
Adenocarcinoma Originating from a Mature Teratoma of the Testis
Kaohsiung Journal of Medical Sciences, 2007 Malignant transformation in testicular teratomas has been reported very rarely in the literature. Although testicular teratomas in childhood are regarded as benign neoplasms, these tumors, if left untreated until advanced ages, may present the risk of ...
Resit Dogan Koseoglu +5 more
doaj +1 more source
Dietary Patterns and Risk of Colorectal Cancer Subtypes Classified by Fusobacterium nucleatum in Tumor Tissue [PDF]
, 2018 Importance—Fusobacterium nucleatum appears to play a role in colorectal carcinogenesis through suppression of host immune response to tumor. Evidence also suggests that diet influences intestinal F. nucleatum. However, the role of F.
Bullman, Susan +23 more
core +1 more source
The role of optical and virt ual colonoscopy in colorectal neoplasms [PDF]
, 2015 Purpose: High prevalence of colon carcinoma explains the continued high mortality rate of this disease.Utilizing a strategy of virtual colonoscopy (VC) in patients aged over 50 years with optical colonoscopy (OC) following-up for removal of detected ...
Bozhkov, V. +5 more
core +2 more sources
Molecular Oncology, EarlyView.Dinaciclib blocks CDK12 activity, leading to downregulation of BRCA1, and probably other proteins involved in homologous recombination, promoting nonhomologous end joining. In this scenario, the presence of ionising radiation triggers a p53‐dependent senescent response that yields increased radiosensitivity. Pan‐cyclin‐dependent‐kinase (CDK) inhibitors
Natalia García Flores +14 more
wiley +1 more source
Atypia and Surface Structure of Superficial Neoplasms of the Colon Less Than 10 mm in Diameter [PDF]
, 1996 Histological specimens of 30 distinct adenomas and 30 distinct carcinomas were studied by image analysis to quantify nuclear size and shape. These data were used to derive a discriminant equation, which permitted the lesions to be classified into two ...
Yasuda, Masatoshi
core +3 more sources
Molecular Oncology, EarlyView.The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits +7 more
wiley +1 more source
Cancer Medicine, 2019 Purpose This study aimed to investigate the characteristics of colonic neuroendocrine neoplasms (NENs) and to validate the prognostic value of the European Neuroendocrine Tumor Society (ENETS) and American Joint Committee on Cancer (AJCC) 8th staging ...
Yu Zhang +22 more
doaj +1 more source
On tumor development: fractional transport approach [PDF]
arXiv, 2004 A growth of malignant neoplasm is considered as a fractional transport approach. We suggested that the main process of the tumor development through a lymphatic net is fractional transport of cells. In the framework of this fractional kinetics we were able to show that the mean size of main growth is due to subdiffusion, while the appearance of ...
arxiv
Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis
Molecular Oncology, EarlyView.Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch +11 more
wiley +1 more source