Results 121 to 130 of about 185,360 (305)

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Telomerase activity of normal tissues and neoplasms in rat colon carcinogenesis induced by methylazoxymethanol acetate and its difference from that of human colonic tissues [PDF]

, 1996
Naoki Yoshimi, Natsuko Ino, Masumi Suzui, Akira Hara, Kei Nakatani, Suzuyo Sato, Hideki Mori   +6 more
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Importance of extracolonic findings at IV contrast medium-enhanced CT colonography versus those at non-enhanced CT colonography [PDF]

, 2018
To compare the clinical importance of extracolonic findings at intravenous (IV) contrast-enhanced CT colonography versus those at non-enhanced CT colonography.
Dinkel, Hans-Peter, Hoppe, Hanno, Mattich, Joerg, Netzer, Peter, Spreng, Adrian, Vock, Peter   +5 more
core  

Minilaparotomias para tratamento de doenças do cólon

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Estudar as possibilidades técnicas e resultados obtidos com pequenas incisões para tratar doenças do cólon. MÉTODO: Vinte e seis pacientes, 12 do sexo masculino e 14 do feminino foram submetidos a laparotomias com incisões menores que 10cm.
Peretz Capelhuchnik, Paulo de Azeredo Passos Candelária, Chia Bin Fang, Wilmar Artur Klug, Jorge Alberto Ortiz   +4 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Perivascular Epithelioid Cell Tumor (PEComa) of the Sigmoid Colon: Case Report and Literature Review

Current Oncology
Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms characterized by perivascular epithelioid cell proliferation. They can occur in various organs, but colonic PEComas are exceptionally rare, showing diagnostic challenges due to
Gintare Slice, Rokas Stulpinas, Tomas Poskus, Marius Kryzauskas   +3 more
doaj   +1 more source

Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice [PDF]

, 2004
Jesper Thulesen
openalex   +1 more source

Fungal Infection Masquerading as a Colonic Neoplasm

, 2021
Raghunath Babu G V S
openalex   +2 more sources