Results 231 to 240 of about 48,552 (289)

A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer

Advanced Science, EarlyView.
The hierarchical organization of the eukaryotic genome is vital for nuclear function, and disruptions from genetic mutations can alter this 3D architecture. Cataloging thousands of interchromosomal translocations, structural variants, and single nucleotide polymorphisms, their impact on 3D genome organization is revealed. The scoring algorithm, 3DFunc,
Li Tang, Matthew C. Hill, Mingxing He, Junhao Chen, Zirui Wang, Patrick T. Ellinor, Min Li   +6 more
wiley   +1 more source

Genetic analysis for diagnosing local recurrence of sigmoid colon cancer mimicking a small intestinal tumor: a case report. [PDF]

World J Surg Oncol
Ito G, Ota Y, Yamaguchi K, Furukawa Y, Mochizuki S, Ahiko Y, Shida D.   +6 more
europepmc   +1 more source

Specific expression of tenascin in human colonic neoplasms

, 1993
Takao Sakai, Hisaaki Kawakatsu, Norio Hirota, Takeshi Yokoyama, Teruyo Sakakura, Masaki Saito   +5 more
openalex   +2 more sources

PCSK9 Promotes the Malignancy of Triple‐negative Breast Cancer Cells by Reducing Cholesterol Levels at the Plasma Membrane to Activate EGFR and HER3

Advanced Science, EarlyView.
By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley   +1 more source

Robotic-assisted versus laparoscopic surgery for colorectal cancer in high-risk patients: a systematic review and meta-analysis. [PDF]

Tech Coloproctol
Gahunia S, Wyatt J, Powell SG, Mahdi S, Ahmed S, Altaf K.   +5 more
europepmc   +1 more source

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

Advanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang, Qiang Tian, Zhenli Lei, Shuxin Wang, Nan Cheng, Zhen Wang, Xianqin Jiang, Xuqun Zheng, Wenjing Xu, Minyan Ye, Longwei Zhao, Meiyun Wen, Jianlou Niu, Weijian Sun, Pingping Shen, Zhifeng Huang, Xiaokun Li   +16 more
wiley   +1 more source

The association between colonic diverticulosis and colorectal polyps in a retrospective cohort study. [PDF]

Int J Colorectal Dis
Altıner S, Aydoğdu YF, Kosmaz K, Durhan A, Senlikci A, Suleyman M, Ersak C, Pekcici MR.   +7 more
europepmc   +1 more source

Genome‐Wide Silencer Screening Reveals Key Silencer Modulating Reprogramming Efficiency in Mouse Induced Pluripotent Stem Cells

Advanced Science, EarlyView.
This study utilized Ss‐STARR‐seq to construct a genome‐wide silencer map of mouse cells and elucidated the fundamental characteristics of these silencers. These silencers exist in a cell‐specific manner and exhibit unique epigenetic modifications. Through functional experiments, we also discovered that these silencers can regulate gene expression and ...
Xiusheng Zhu, Lei Huang, Guoli Li, Biao Deng, Xiaoxiao Wang, Hu Yang, Yuanyuan Zhang, Qiuhan Wen, Chao Wang, Jingshu Zhang, Yunxiang Zhao, Kui Li, Yuwen Liu   +12 more
wiley   +1 more source

Intracerebral Solitary Fibrous Tumor in Collision With Metastatic Colonic Adenocarcinoma. [PDF]

Cureus
Le BH, Konar S, Barr RM, Imbarrato GJ.
europepmc   +1 more source

Colonic-Type Adenocarcinoma of the Base of the Tongue: A Case Report of a Rare Neoplasm

, 2011
Denisa Slova, Alberto Paniz Mondolfi, Ioana Moisini, Gabriel Levi, Mark L. Urken, José P. Zevallos, Sharmeen Mansoor, Azita S. Khorsandi, Dov C. Bloch, Ramapriya Vidhun, Bruce M. Wenig   +10 more
openalex   +2 more sources