Results 261 to 270 of about 185,360 (305)
Large colonic lipomas presenting as a rare cause of adult bowel obstruction and intussusception: A two-case surgical series. [PDF]
Habte YM +5 more
europepmc +1 more source
FBXO44 promotes colorectal cancer progression by targeting FOXP1 for ubiquitin‐mediated degradation. This study reveals a phosphorylation‐dependent mechanism involving AURKA and highlights the FBXO44/FOXP1/Cyclin E2 axis as a potential therapeutic target in colorectal cancer.
Hongxu Nie +10 more
wiley +1 more source
Postpartum colonic squamous cell carcinoma with a BRAF<sup>V600E</sup> mutation: a case report. [PDF]
Wang Q +5 more
europepmc +1 more source
Steroid receptor coactivator‐1 (SRC‐1) reprograms tumor‐associated macrophages (TAMs) via signal transducer and activator of transcription 1(STAT1)‐mediated matrix metallopeptidase 12 (MMP12) transcription to drive perineural invasion (PNI) in pancreatic cancer.
Ke Cheng +9 more
wiley +1 more source
A Case of APC Gene Mutation-Associated Familial Adenomatous Polyposis With Multiple System Malignancies. [PDF]
Yijing R +6 more
europepmc +1 more source
Okanin Suppresses the Growth of Colorectal Cancer Cells by Targeting at Peroxiredoxin 5
Okanin suppresses colorectal cancer growth by directly targeting PRDX5. This natural compound selectively binds peroxiredoxin 5 (PRDX5), inhibiting its activity and inducing WSB1‐mediated degradation. PRDX5 loss elevates ROS, suppresses GPX4 via SIAH2, and further triggers cell death (apoptosis and ferroptosis).
Ji Zhong Zhao +9 more
wiley +1 more source
Schwannoma of the colon presenting as a submucosal lesion: diagnostic challenge and surgical management. [PDF]
Al Yaseen M +5 more
europepmc +1 more source
Skullcapflavone II (SkII) significantly alters serine metabolism in gastric cancer cells by directly targeting the L‐serine transporter SLC1A4, thereby inhibiting L‐serine uptake rather than de novo synthesis. This disruption of serine metabolism by SkII leads to increased oxidative stress and consequent mitochondrial damage.
Jing Zhao +10 more
wiley +1 more source
The emperor has no clothes-the need for standardized anatomical segment definitions in the management of colon cancer. [PDF]
Kutlu B +4 more
europepmc +1 more source

