Results 51 to 60 of about 322,350 (298)

Colonic Protein Fermentation and Promotion of Colon Carcinogenesis by Thermolyzed Casein [PDF]

, 1995
Thermolyzed casein is known to promote the growth of aberrant crypt foci (ACF) and colon cancer when it is fed to rats that have been initiated with azoxymethane.
Thompson, Lilian, Bruce, W. Robert, Archer, Michael C., Rémésy, Christian, Medline, Alan, Corpet, Denis E.   +5 more
core  

Add-on to current guidelines for monitoring of SBS patients treated with teduglutide

npj Gut and Liver
By inducing growth of the intestinal epithelium, the drug teduglutide, used for the treatment of short bowel syndrome-associated intestinal failure, could feasibly promote growth of pre-existing colonic neoplasms and incite the development of new ones. A
Francisca Joly, Johane P. Allard, Gabriel E. Gondolesi, Palle Bekker Jeppesen, Martina Kohl-Sobania, Ulrich-Frank Pape, Loris Pironi, Lauren K. Schwartz, Joel Mason   +8 more
doaj   +1 more source

Perivascular epithelioid cell neoplasm of the colon

World Journal of Gastrointestinal Oncology, 2010
A 17-year-old female presented with rectal bleeding from an ulcerated sigmoid mass in 1994. Initial pathological evaluation revealed a rare clear cell neoplasm of the colon, possibly originating from kidneys, adrenals, lung or a gynecologic source as a metastatic lesion.
Hugh James, Freeman, Doug L, Webber
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Preoperative localization of potentially invisible colonic lesions on the laparoscopic operation field: using autologous blood tattooing [PDF]

Annals of Coloproctology
Purpose Preoperative colonoscopic (POC) localization is recommended for patients scheduled for elective laparoscopic colectomy for early colon cancer. Among the various localization method, POC tattooing localization has been widely used.
Ji Yeon Mun, Hyunjoon An, Ri Na Yoo, Hyeon-Min Cho, Bong-Hyeon Kye   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Persistence of anticancer activity in berry extracts after simulated gastrointestinal digestion and colonic fermentation [PDF]

, 2012
Fruit and vegetable consumption is associated at the population level with a protective effect against colorectal cancer. Phenolic compounds, especially abundant in berries, are of interest due to their putative anticancer activity.
Allsopp Philip, Magee Pamela, González-Barrio, Rocio, Rocio González-Barrio (117854), McDougall, Gordon J., Gill, Chris I. R., Philip Allsopp (117857), Ian Rowland (117868), Gordon J. McDougall (117848), Gema Pereira-Caro (117851), Derek Stewart, Gema Pereira-Caro, McDougall Gordon J., Crozier Alan, Magee, Pamela, McDougall, G.J., Pamela Magee (117861), Philip Allsopp, Pamela Magee, Stewart Derek, Gordon J McDougall, Pereira-Caro, Gema, Gill Chris I. R., Stewart, D., Ian Rowland, Brown, E.M., Alan Crozier (117865), Brown Emma M., Gill, C.I.R., Pereira-Caro Gema, Derek Stewart (117849), Stewart, Derek, González-Barrio, R., Rowland, Ian, Pereira Caro, G., Emma M. Brown (117847), Rowland Ian, Rocio González-Barrio, Chris I R Gill, Pereira-Caro, G., Alan Crozier, Magee, P., Allsopp, P., González-Barrio, R, Crozier, A., Rowland, I., González-Barrio Rocio, Allsopp, Philip, Emma M Brown, Chris I. R. Gill (117871), Brown, Emma M., Crozier, Alan   +51 more
core   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

MYOD-1 in normal colonic mucosa : role as a putative biomarker? [PDF]

, 2012
Background DNA methylation of promoter-associated CpG islands of certain genes may play a role in the development of colorectal cancer. The MYOD-1 gene which is a muscle differentiation gene has been showed to be significantly methylated in colorectal ...
Mathers, John, Arasaradnam, Ramesh P, Arasaradnam, Ramesh P., Commane, Daniel M., Mathers John C, Quraishi, M. N., Quarashi, Nabil, Bradburn, Mike, Quraishi, M. Nabil, Bradburn Mike, Mathers, John C, Arasaradnam, Ramesh, Quraishi M, Commane, Danny, Commane, Daniel, Arasaradnam Ramesh P, Mathers, John C., Quraishi, M Nabil, Commane Daniel   +18 more
core   +1 more source

Uncommon Presentations of Pancreatic Neoplasms, Rare Neoplasms, and Peripancreatic Masses

, 2022
Pancreatic masses with atypical radiological appearance are frequently encountered. Atypical presentation of common pancreatic tumor is also possible.
Antonia Olivieri, Roberto Calbi, Paola Capelli, Angela Calabrese, Paolo Tinazzi Martini, Nicolò Cardobi, Mirko D’Onofrio, Riccardo De Robertis, Luca Geraci   +8 more
core   +1 more source