Results 31 to 40 of about 181,307 (259)

Epiplakin expression dynamics during colon carcinogenesis: Correlation with proliferation

Biomolecules & Biomedicine
Colorectal cancer poses a significant global health challenge, with a considerable proportion arising from colon adenomas. Understanding the molecules involved in the carcinogenesis process is crucial for improving colon cancer diagnosis and prognosis ...
Damla Gül Fındık, Erhan Şahin, Özlem Türelik, Gürkan Güneri   +3 more
doaj   +1 more source

Potential benefit of superior to inferior dissection during laparoscopic extended right hemicolectomy

Journal of Minimally Invasive Surgery, 2022
Various approaches can be used for performing laparoscopic right hemicolectomy for right-sided colon cancer. However, laparoscopic complete mesocolic excision with central vessel ligation using these approaches may sometimes present with difficulties of ...
Dae Ro Lim
doaj   +1 more source

Colonization of epithelial pilar neoplasms by melanocytes [PDF]

Histopathology, 2005
  We retrieved 50 cutaneous epithelial pilar neoplasms from The Royal London Hospital archives (1980–2003), 46 benign (39 trichoepitheliomas ⁄ seven trichoblastomas) and four malignant (trichilemmal carcinomas). The pilar differ- entiation criteria included organoid, lobular or folli- culo-centric growth pattern, few or no connections with the ...
Diaz-Cano, Salvador J., L Pozo-Garcia, Z Aly   +2 more
openaire   +2 more sources

Adenocarcinoma do colon revelado por endocardite por estreptococos bovis.

Acta Médica Portuguesa, 1992
The association of Streptococcus bovis endocarditis with colonic neoplasms has been well documented. We describe a patient in whom the finding of a Str. bovis endocarditis stimulated investigation which resulted in the diagnosis and surgical treatment of
J Almeida, J Bau, I Baptista, T Matias, J Quininha, J M Bentes-Jesus, A Vital-Morgado   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A Colonic Perineurioma

Clinical Medicine Insights: Pathology, 2018
Perineurioma is a mesenchymal neoplasm best known in soft-tissue pathology. A colonic perineurioma is a relatively recently described entity and sometimes encountered in specimens from the large intestine, especially distal colon. Without its recognition,
Tomoyuki Otani, Kinta Hatakeyama, Emi Ohtani, Susumu Nakayama, Takashi Fujimoto, Chiho Ohbayashi   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Add-on to current guidelines for monitoring of SBS patients treated with teduglutide

npj Gut and Liver
By inducing growth of the intestinal epithelium, the drug teduglutide, used for the treatment of short bowel syndrome-associated intestinal failure, could feasibly promote growth of pre-existing colonic neoplasms and incite the development of new ones. A
Francisca Joly, Johane P. Allard, Gabriel E. Gondolesi, Palle Bekker Jeppesen, Martina Kohl-Sobania, Ulrich-Frank Pape, Loris Pironi, Lauren K. Schwartz, Joel Mason   +8 more
doaj   +1 more source