Results 81 to 90 of about 185,360 (305)

A Case of Myeloid Sarcoma of Intestine

The Korean Journal of Gastroenterology, 2016
Myeloid sarcoma (MS) is an extramedullary involvement of immature myeloid proliferation. An isolated MS is defined as a myeloblastic tumor when it arises without any concomitant circulating disease.
Sung Won Lim, Hang Lak Lee, Kang Nyeong Lee, Dae Won Jun, In Young Kim, Eunjin Kim, Hyein Ahn, Chan Kum Park   +7 more
doaj   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Endoscopic submucosal dissection vs laparoscopic colorectal resection for early colorectal epithelial neoplasia [PDF]

, 2015
published_or_final_versio
Chiu, PW, Hon, SS, Lee, JF, Leung, WW, Mak, TW, Ng, SS, Wong, CLT   +6 more
core   +1 more source

Pedunculated Cecal Lipoma Causing Colo-Colonic Intussusception: A Rare Case Report

Case Reports in Surgery, 2012
Colonic lipomas are uncommon nonepithelial neoplasms that are typically sessile, asymptomatic and incidentally found during endoscopy, surgery, or autopsy.
Stefanos Atmatzidis, Grigoris Chatzimavroudis, Aristidis Patsas, Basilis Papaziogas, Spiros Kapoulas, Stelios Kalaitzis, Ananias Ananiadis, John Makris, Konstantinos Atmatzidis   +8 more
doaj   +1 more source

Intussusception Caused by Colon Cancer in Pregnancy

The Korean Journal of Gastroenterology, 2019
Intussusception is a common in pediatric age group. But it is rare in adults. And intussusception caused by tumor account for 1% of bowel obstructions in adult. Intussusception is an extremely rare cause of abdominal pain in pregnancy.
Kyungjoong Kim, Myungkwan Ko, Ho Chan Sim, Chang Lae Kim, Yeo Jin Jung, Tae Oh Kim   +5 more
doaj   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-β in colorectal cells. [PDF]

, 2012
Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors.
Fu, Lei, He, Yu-qi, Jin, Peng, Ling, Xian-long, Rao, Jianyu, Sheng, Jian-qiu, Yen, Lawrence   +6 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Colon lesions in elderly individuals with positive and negative fecal immunochemical test results among PERSIAN Guilan cohort study (PGCS) population [PDF]

Caspian Journal of Internal Medicine
Background: Early colorectal cancer (CRC) detection helps reduce the mortality rate. This study aimed to investigate colon lesions in individuals with positive and negative fecal immunochemical test (FIT) results among the (PERSIAN) Guilan cohort study ...
Heydar Ali Balou, Farahnaz Joukar, Mahdi Orang Goorabzarmakhi, Milad Shahdkar, Soheil Hassanipour, Saman Maroufizadeh, Mehrnaz Asgharnezhad, Paridokht Karimian, Fariborz Mansour-Ghanaei   +8 more
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source