Results 61 to 70 of about 151,392 (289)
Results of total colonoscopy in the diagnosis of polyps. Case studies in Villavicencio, Colombia
Revista de la Facultad de Medicina, 2017 Introduction: Any elevation above the normal plane of the colonic mucosa is considered a polypoid projection. As age increases, polyps are more likely to be found; in addition, polyps larger than 1 cm of diameter may potentially lead to a malignant ...
Mauricio Alberto Melo-Peñaloza
doaj +1 more source
KRAS and BRAF somatic mutations in colonic polyps and the risk of metachronous neoplasia. [PDF]
PLoS ONE, 2017 High-risk features of colonic polyps are based on size, number, and pathologic characteristics. Surveillance colonoscopy is often recommended according to these findings. This study aimed to determine whether the molecular characteristics of polyps might
Miriam Juárez +17 more
doaj +1 more source
Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia : a case-control and immunohistochemical study [PDF]
, 2012 PMID: 22824379 [PubMed - indexed for MEDLINE] PMCID: PMC3500224 Free PMC ArticlePeer reviewedPublisher ...
Basavaraju, Umesh +6 more
core +1 more source
Advanced Science, EarlyView.This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou +9 more
wiley +1 more source
The Saudi Journal of Gastroenterology, 2021 Background: Endoscopic removal of large and thick-stalked pedunculated colonic polyps, often leads to massive hemorrhage. Several techniques to minimize this complication have not been widely adopted due to some caveats.
Hyun Ho Choi +6 more
doaj +1 more source
Advanced Science, EarlyView.CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu +13 more
wiley +1 more source
The Importance of CT Pneumocolon in Detecting Colonic Lesions
Diyala Journal of Medicine, 2021 Background: Colonic masses are clinically important because some of them are malignant and others have a tendency to become malignant such as polyps. CT pneumocolon may have a role in the evaluation and diagnosis of these masses.
Saadoonsen Zghair Haidar Al –Yas +2 more
doaj +2 more sources
Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery
Advanced Science, EarlyView.Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra +6 more
wiley +1 more source
Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system. [PDF]
, 2003 The Apc(Min/+) mouse model and the azoxymethane (AOM) rat model are the main animal models used to study the effect of dietary agents on colorectal cancer. We reviewed recently the potency of chemopreventive agents in the AOM rat model (D. E.
Corpet, Denis E., Pierre, Fabrice
core +2 more sources
Development of an Ex Vivo Organ Culture Technique to Evaluate Probiotic Utilization in IBD [PDF]
, 2016 The consistent technical and conceptual progress in the study of the microbiota has led novel impulse to the research for therapeutical application of probiotic bacteria in human pathologies, such as inflammatory bowel disease (IBD).
DELLE FAVE, Gianfranco +3 more
core +1 more source