Results 141 to 150 of about 36,381 (232)

Consequences of <i>Campylobacter jejuni</i> and <i>Campylobacter coli</i> Colonisation of Piglets on Gut Microbiota and Microbial Metabolites. [PDF]

Microorganisms
Rath A, Rautenschlein S, Rzeznitzeck J, Lalk M, Methling K, Karasova D, Rychlik I, Waldmann KH, Altrock AV.   +8 more
europepmc   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Symbiotic phosphate transporter dynamics in rice expose functional plasticity of the arbuscules. [PDF]

Nat Commun
McGaley J, Orvošová M, Schneider B, Chiu CH, Roth R, Bowden S, Hope MS, Davis JL, Khalif W, Wallington EJ, Paszkowski U.   +10 more
europepmc   +1 more source

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

Advanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li, Yonglong Li, Jiren Yan, Changming Wang, Jinlong Yu, Feng Jiang, Boyong Wang, Yi Yang, Deyi Ding, Jin Tang, Pei Han, Botao Song, Geyong Guo, Hao Shen   +13 more
wiley   +1 more source

Intrapartum Molecular Detection of Group B <i>Streptococcus</i>: Real-World Evaluation of Multiple Point-of-Care Platforms and the Potential Role of Lysis Efficiency. [PDF]

Microorganisms
Serrari M, Bianchi L, Tré-Hardy M, Törnblom-Paulander S, Alexandre M, Nevraumont A, Beukinga I, Buxant F, Bensaoud H, Blairon L.   +9 more
europepmc   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

Risk-Based Pre-Admission Screening for Carbapenem-Resistant Enterobacterales (CRE): A Patient-Level Observational Study in a High-Endemic European Setting. [PDF]

Microorganisms
Altavilla S, Loconsole D, Di Pietro N, Memmola R, Sivo D, Di Gennaro F.   +5 more
europepmc   +1 more source

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Seasonality and other factors influencing hospital acquisition of multi-drug-resistant Enterobacterales colonisation: a one-year cohort study - Botswana, 2022-2023. [PDF]

Infect Prev Pract
Ntereke TD, Lechiile K, Mannathoko N, Mokgwathi K, Tlhako N, Moorad B, Zankere T, Gatonye T, Mokomane M, Mosepele M, Cancedda C, Richard-Greenblatt M, John-Thubuka J, Goldfarb D, Styczynski A, Parra G, Smith RM, Lautenbach E, Strysko J.   +18 more
europepmc   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

Advanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang, Fen Xiong, Yiwen Peng, Lingfei Meng, Xinran Wang, Yingruo Xu, Tian Tang, Hongchang Gao   +7 more
wiley   +1 more source