Results 151 to 160 of about 103,362 (272)

De la colonisation de l'Algérie /

open access: yes
Extract from Bugeaud's brochure "Quelques considérations sur trois questions fondamentales de notre établissement en Algérie," p.
Bugeaud, Thomas Robert, duc d'Isly, 1784-1849.
core  

Géographie, exploration et colonisation

open access: yes, 2005
Séminaire : Géographie, exploration et colonisation Maison des Sciences de l'Homme d'Aquitaine/Pessac 10, Espanade des Antilles 33 607 Pessace 13, 14 et 15 octobre 2005 jeudi 13 octobre Introduction 14 h · Allocution de Christophe Bouneau ...

core  

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

open access: yesAdvanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo   +10 more
wiley   +1 more source

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang   +5 more
wiley   +1 more source

Contribution de l’hôpital militaire dans la structuration et l’évolution de la ville coloniale. Cas de la Ville de Laghouat

open access: yesRevue d'Histoire Méditerranéenne
Le 4 Décembre 1852, l'armée française détruira le Ksar de Laghouat qui deviendra la base d'une ville nouvelle. Cette ville obéira à de nouvelles règles d'urbanisme.
MAGHMOULI Hanane.
doaj  

Hypomethylation of GNA15 Promotes Pancreatic Ductal Adenocarcinoma Progression and Macrophage M2 Polarization via STAT3‐CXCL8 Axis

open access: yesAdvanced Science, EarlyView.
A schematic model summarizing GNA15's mechanism in mediating macrophage M2 polarization and Gemcitabine resistance. ABSTRACT The complexity of pancreatic ductal adenocarcinoma (PDAC) progression, coupled with the lack of effective immunotherapy, underscores the imperative to deepen our understanding of its mechanisms and identify suitable immune ...
Weihui Guo   +8 more
wiley   +1 more source

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

open access: yesAdvanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu   +4 more
wiley   +1 more source

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