Results 191 to 200 of about 120,934 (309)

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

open access: yesCell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar   +5 more
wiley   +1 more source

Anti‐Integrin αvβ6 Autoantibodies as Diagnostic and Monitoring Biomarkers for Pediatric‐Onset Primary Sclerosing Cholangitis

open access: yesHepatology Research, EarlyView.
Levels of anti‐integrin αvβ6 antibodies were significantly higher in pediatric‐onset primary sclerosing cholangitis (PSC) than in autoimmune hepatitis (AIH) and may reflect disease activity. These antibodies may serve as a novel biomarker for distinguishing PSC from AIH and for monitoring disease progression.
Yukako Maeda   +17 more
wiley   +1 more source

Current Status of Bowel Preparation for Colonoscopy in Japan: A Web-Based Survey of Endoscopists (PRESS Survey). [PDF]

open access: yesDEN Open
Matsumoto T   +8 more
europepmc   +1 more source

Traditional serrated adenoma of the colorectum: Evolving concepts in histological classification and terminology

open access: yesHistopathology, EarlyView.
The definition of the colorectal traditional serrated adenoma (TSA) has evolved to recognize a broader morphological spectrum, including classical, flat and mixed lesions reflecting early development and neoplastic progression. Updated WHO classification highlights the need for consistent terminology to improve recognition and to distinguish TSA from ...
Christophe Rosty   +7 more
wiley   +1 more source

Tigecycline combination therapy for fulminant Clostridioides difficile infection: an Australian experience

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Recent European Society of Clinical Microbiology and Infection and Australasian Society of Infectious Diseases Clostridioides difficile infection (CDI) management guidelines endorse the addition of intravenous tigecycline in patients who are progressing to fulminant infection.
Emma Bishop   +5 more
wiley   +1 more source

Does Everyone Need CEA? A Case for Selective Omission After Colorectal Cancer Resection

open access: yes
ANZ Journal of Surgery, EarlyView.
Matthew P. Irwin   +3 more
wiley   +1 more source

Self‐Directed Mikoto Simulator Training for Colonoscopy in Gastroenterology Trainees: An International Multicenter Randomized Trial

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Objectives Simulation‐based colonoscopy training may support early acquisition of insertion skills, but its clinical effect remains uncertain. We evaluated whether a self‐directed curriculum using the mikoto colonoscopy simulator improved insertion performance in gastroenterology trainees.
Daisuke Yamaguchi   +23 more
wiley   +1 more source

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