Sustained gene expression in the retina by improved episomal vectors [PDF]
, 2014 Gene and cellular therapies are nowadays part of therapeutic strategies for the treatment of diverse pathologies. The drawbacks associated with gene therapy-low levels of transgene expression, vector loss during mitosis, and gene silencing-need to be ...
Ana V. Oliveira +7 more
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Antisense PNA accumulates in Escherichia coli and mediates a long post-antibiotic effect [PDF]
, 2007 Antisense agents that target growth-essential genes display surprisingly potent bactericidal properties. In particular, peptide nucleic acid (PNA) and phosphorodiamidate morpholino oligomers linked to cationic carrier peptides are effective in time kill ...
Behmanesh, Mehrdad +9 more
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Pharmaceutical Biology, 2017 Context: Equisetum giganteum L. (Equisetaceae) is an endemic plant of Central and South America used in traditional medicine. Natural drugs have been frequently used in the treatment of a myriad of diseases, proving to be an alternative to synthetic ...
Rafaela Alves da Silva +4 more
doaj +1 more source
A Sensitive DNA Enzyme-Based Fluorescent Assay for Bacterial Detection
Biomolecules, 2013 Bacterial detection plays an important role in protecting public health and safety, and thus, substantial research efforts have been directed at developing bacterial sensing methods that are sensitive, specific, inexpensive, and easy to use.
Yingfu Li +3 more
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Detection and characterisation of Complement protein activity in bovine milk by bactericidal sequestration assay [PDF]
, 2015 Susan Maye is in receipt of a Teagasc Walsh Fellowship. Financial support by the Department of Agriculture, Food and the Marine is gratefully acknowledged.Copyright © Proprietors of Journal of Dairy Research 2015 (Institute of Food Research and the ...
Fitzgerald, Gerald F +3 more
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Colony-forming unit assay as a potency test for hematopoietic stem/progenitor cell products
Molecular and experimental biology in medicine, 2019 Colony-forming unit (CFU) assay is a short-term culture assay used for the detection of functionally active hematopoietic progenitor cells (HPCs) in the in vitro setting. This potency assay enables the identification of colony-producing HPCs in any type of hematopoietic stem cell/progenitor product (HSC/P) including bone marrow (BM), cord blood (CB ...
Skific, Marijana, Golemovic, Mirna
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Value of colony forming unit-granulocyte macrophage assay in predicting relapse in acute myeloid leukaemia. [PDF]
Journal of Clinical Pathology, 1996 AIM: To evaluate the validity of the colony forming unit-granulocyte macrophage (CFU-GM) assay for predicting relapse in patients with acute myeloid leukaemia (AML). METHODS: The study population comprised 32 patients with AML in remission, followed for a median of 18 months. A mean of four studies was carried out per patient.
M C, del Cañizo +6 more
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Functional Assessment of Cord Blood Units Using Two Different Assays
International Journal of Hematology-Oncology and Stem Cell Research, 2012 Background : The cord blood banks and cord blood transplantation community are on the constant lookout for a single objective dependable test that will indicate the functional capabilities of the cord blood units. This should ideally reflect engraftment,
Chandra Viswanathan +8 more
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Impact of sitagliptin on endometrial mesenchymal stem-like progenitor cells : a randomised, double-blind placebo-controlled feasibility trial [PDF]
, 2020 Background: Recurrent pregnancy loss (RPL) is associated with the loss of endometrial mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and engraftment of bone marrow-derived cells to sites of tissue injury.
Brighton, Paul (Paul J.) +13 more
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Colony-Forming Unit Spreadplate Assay versus Liquid Culture Enrichment-Polymerase Chain Reaction Assay for the Detection of Bacillus Endospores in Soils [PDF]
Geosciences, 2019 A liquid culture enrichment-polymerase chain reaction (E-PCR) assay was investigated as a potential tool to overcome inhibition by chemical component, debris, and background biological impurities in soil that were affecting detection assay performance for soil samples containing Bacillus atrophaeus subsp. globigii (a surrogate for B. anthracis).
Griffin, Dale W. +3 more
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