Results 61 to 70 of about 392,683 (226)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Efficacy of Nanosil and Listerine Antiseptics for Infection Control in Dental Unit Waterline

Journal of Dental School, 2020
Objectives The aim of this study was to compare the antibacterial efficacy of two antiseptic agents namely Nanosil and Listerine for controlling water contamination.
Neda Omidpanah, Farideh Najafi, Ramin Abiri   +2 more
doaj   +1 more source

The counting of surface colonies of bacteria [PDF]

Epidemiology and Infection, 1948
A colony count performed by spreading a known volume of suspension on the surface of a plate possesses certain advantages over other methods, of which the chief is ease of counting.The distribution of counts of several samples of the same suspension on medium of the same age and batch is as expected on statistical grounds.Different batches and ages of ...
openaire   +2 more sources

Colony Counts on Strips of Agar in Tubes [PDF]

Journal of General Microbiology, 1950
SUMMARY: For viable counting, 0.1 ml. volumes of bacterial suspension were incorporated in 1.5-2 ml. nutrient agar, which after mixing was allowed to solidify in an almost horizontal test-tube so as to produce a 3–4 in. agar strip. After incubation in the vertical position, the counts of the strips gave estimates of a bacterial population which did not
A C, STIRLING, M K, STEVENS, D N, LAWLEY
openaire   +2 more sources

A cell line derived from BBN (N-butyl-N-[4-hydroxybutyl]-nitrosamine)-induced rat bladder cancer: establishment and scanning electron microscopic cell surface characteristics [PDF]

, 1978
This research was performed to establish a cell line from experimental bladder tumor and to discuss the biological characteristics of the cell line so established. Tissue cultures of epithelial cells were derived from a rat bladder cancer induced by BBN.
Nishi, Mitsuo
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Changes in quality of Liaoning Zhuanghe Dagu chicken jerky at different storage temperatures and establishment of shelf life prediction model

Shipin yu jixie
ObjectiveTo investigate the changes in the quality of Dagu chicken jerky during storage at different temperatures and establish a shelf-life prediction model based on thiobarbituric acid reactive substance (TBARS) value and colony count.MethodsThe Dagu ...
JIN Na, YAN Ruichi, SU Yuhong, WANG Xizhu, SHANG Hongli   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Effects of Processing and Preservation Technologies on Keeping Quality of Labeo rohita: Attributes of Nutritional, Microbial and Sensory [PDF]

Journal of Food Quality and Hazards Control
Background: Fishes being major sources of protein are susceptible to post-harvest losses. Appropriate processing and preservation makes food healthier, safer, tastier, and more shelf-stable. Therefore, an attempt was made to evaluate the effectiveness of
M.S. Arefin, S. Akther, N. Rahman, M. Begum, N. Sarwar   +4 more
doaj