Results 91 to 100 of about 68,467 (248)
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
BiologyBougainvillea has large and vibrant-colored bracts, which are widely used in landscape gardening. In order to study the changing pattern of pigmentation and the expression of genes related to pigment synthesis during different developmental periods of ...
Xiangdong Liu +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Phyllomedusa: Journal of Herpetology, 2012 We studied the various color morphsof Dendrobates galactonotus that occur in its range between the Amazon and Tapajósrivers, in the Brazilian states of Pará, Maranhão, northern Mato Grosso, and northernTocantins.
Marinus S. Hoogmoed +1 more
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Journal of CO2 UtilizationAn efficient and ecofriendly method to remove impurities from raw cashmere fiber was constructed by employing various biological enzymes (lipase, cellulase, pectinase and protease) to form reverse microemulsion in supercritical carbon dioxide.
Fan Wang +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The pseudo-type response regulator gene Clsc regulates rind stripe coloration in watermelon
Journal of Integrative AgricultureThe color and pattern of watermelon rind are crucial external traits that directly affect consumer preferences. Watermelons with stripes having a stronger color than the background rind are ideal for studying stripe patterns in plants, while there is ...
Dongming Liu +12 more
doaj +1 more source